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A Model of Controlled Growth

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Abstract

We consider a free boundary problem for a system of PDEs, modeling the growth of a biological tissue. A morphogen, controlling volume growth, is produced by specific cells and then diffused and absorbed throughout the domain. The geometric shape of the growing tissue is determined by the instantaneous minimization of an elastic deformation energy, subject to a constraint on the volumetric growth. For an initial domain with \({\mathcal{C}^{2,\alpha}}\) boundary, our main result establishes the local existence and uniqueness of a classical solution, up to a rigid motion.

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Authors and Affiliations

  1. Department of Mathematics, Penn State University, University Park, PA, 16802, USA

    Alberto Bressan

  2. Department of Mathematics, University of Pittsburgh, 301 Thackeray Hall, Pittsburgh, PA, 15260, USA

    Marta Lewicka

Authors
  1. Alberto Bressan
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  2. Marta Lewicka
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Correspondence to Alberto Bressan.

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Communicated by A. Braides

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Bressan, A., Lewicka, M. A Model of Controlled Growth. Arch Rational Mech Anal 227, 1223–1266 (2018). https://doi.org/10.1007/s00205-017-1183-3

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  • DOI: https://doi.org/10.1007/s00205-017-1183-3

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