Abstract
The draft genome sequence and main genomic features of Penicillium pancosmium MUM 23.27, isolated from Portuguese raw honey are reported. The genome size is 34.82 Mb, containing a 48.99% GC content, 11,394 genes, with 39 rRNAs and 147 tRNAs/tmRNAs. Twenty-six BGCs were predicted with four exhibiting significant similarities with YWA1, chaetoglobosin A/chaetoglobosin C, squalestatin S1, and nidulanin A. Moreover, the whole-genome sequencing and in silico genomic analysis, allowed to further understand some aspects of this species habitat, resistance, and evolutionary genomic events. Altogether, the results obtained also allow to dwell deeper on particular Penicillia biological characteristics and genomic traits, permitting them to thrive in these honey substrates. In addition, this resource represents the first genome for the species and one of the first for raw honeys filamentous fungi.
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Acknowledgements
We are grateful to Genoinseq (Cantanhede, Portugal) and IBIMED (Aveiro, Portugal) for the help with the genome sequencing.
Funding
This work was partially carried out in the R&D Unit Centre for Functional Ecology –Science for People & the Planet (CFE), with reference UIDB/04004/2020, and Associate Laboratory TERRA, with reference LA/P/0092/2020, financed by FCT/MCTES through national funds (PIDDAC).
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I.R. and J.T. wrote the main manuscript text. A.P and A. A. check all the cientific anotations. All authors reviewed the manuscript.
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Communicated by Yusuf Akhter.
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Roxo, I., Amaral, A., Portugal, A. et al. Draft genome sequence and comparative genomic analysis of Penicillium pancosmium MUM 23.27 isolated from raw honey. Arch Microbiol 206, 36 (2024). https://doi.org/10.1007/s00203-023-03766-8
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DOI: https://doi.org/10.1007/s00203-023-03766-8