Abstract
Humans and plants have evolved in the near omnipresence of a microbial milieu, and the factors that govern host-microbe interactions continue to require scientific exploration. To better understand if and to what degree patterns between microbial genomic features and host association (i.e., human and plant) exist, I analyzed the genomes of select Burkholderia strains—a bacterial genus comprised of both human and plant-associated strains—that were isolated from either humans or plants. To this end, I uncovered host-specific, genomic patterns related to metabolic pathway potentials in addition to convergent features that may be related to pathogenic overlap between hosts. Together, these findings detail the genomic associations of human and plant-associated Burkholderia strains and provide a framework for future investigations that seek to link host-host transmission potentials.
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I thank Sarah Brand for her input regarding graphic design.
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This work was funded in part by a University of South Carolina SPARC Grant (https://sc.edu/about/offices_and_divisions/research/internal_funding_awards/students/sparc/index.ph) and an PRFB NSF Grant (2109481). The funders did not contribute to the design of the experiments, data collection, analyses, decision to publish, or the preparation of the manuscript.
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Berrios, L. Examining the genomic features of human and plant-associated Burkholderia strains. Arch Microbiol 204, 335 (2022). https://doi.org/10.1007/s00203-022-02953-3
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DOI: https://doi.org/10.1007/s00203-022-02953-3