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Clinical and biological parameters associated with fracture recurrence according to fracture liaison service dataset

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Abstract

Summary

This study describes the characteristics of 337 patients seen by the fracture liaison service of the Amiens University Hospital for at least two osteoporotic fractures between 2009 and 2019. Results showed that recurrent fracture occurs rapidly after the index fracture. Rheumatological and therapeutic managements are not sufficient, mainly because of cognitive disorders or patients’ refusal.

Purpose

The aim of this study was to describe the characteristics of patients taken in charge by a fracture liaison service and sustaining a recurrent osteoporotic fracture.

Methods

This was a retrospective and monocentric study based on the dataset of patients included in the FLS of the Department of Rheumatology of the Amiens University Hospital. To be included in the study cohort, patients must have had at least two consecutive osteoporotic fractures between January 2009 and December 2019.

Results

Three hundred thirty-seven patients were included. The mean age at index fracture was 77.3 ± 12.5 years. Eighty-four percent of the patients were women. 89.3% of the patients had a Charlson comorbidity index between 1 and 4. Nearly half of the patients had cognitive disorders. Femoral neck was the most frequent site for both index and recurrent fractures. Thirty-seven percent of patients benefited from a consultation in Rheumatology after their index fracture. The main reasons for the lack of follow-up were cognitive disorders and patient rejection.

Conclusion

Our study showed that recurrent fracture occurs rapidly after the index fracture and that rheumatological and therapeutic managements are not sufficient, mainly because of cognitive disorders or patients’ refusal impairing the patients to benefit from specialized management.

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Authors and Affiliations

  1. Service de Rhumatologie, Université Picardie Jules Verne, CHU Amiens-Picardie, 80054, Amiens, France

    Marie Doussiere, Claire Jesson, Laetitia Diep, Jimmy Menis, Corinne Fauvet, Patrice Fardellone & Vincent Goëb

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  1. Marie Doussiere
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  2. Claire Jesson
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  3. Laetitia Diep
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  4. Jimmy Menis
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  5. Corinne Fauvet
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  6. Patrice Fardellone
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  7. Vincent Goëb
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Correspondence to Marie Doussiere.

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Doussiere, M., Jesson, C., Diep, L. et al. Clinical and biological parameters associated with fracture recurrence according to fracture liaison service dataset. Osteoporos Int 34, 1977–1982 (2023). https://doi.org/10.1007/s00198-023-06868-7

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  • DOI: https://doi.org/10.1007/s00198-023-06868-7

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