Greater yogurt consumption is associated with increased bone mineral density and physical function in older adults
- 1.4k Downloads
In this cohort of community dwelling older adults (>60 years), we observed significant positive associations between the frequencies of yogurt intake with measures of bone density, bone biomarkers, and indicators of physical function. Improving yogurt intakes could be a valuable health strategy for maintaining bone health in older adults.
The associations of yogurt intakes with bone health and frailty in older adults are not well documented. The aim was to investigate the association of yogurt intakes with bone mineral density (BMD), bone biomarkers, and physical function in 4310 Irish adults from the Trinity, Ulster, Department of Agriculture aging cohort study (TUDA).
Bone measures included total hip, femoral neck, and vertebral BMD with bone biochemical markers. Physical function measures included Timed Up and Go (TUG), Instrumental Activities of Daily Living Scale, and Physical Self-Maintenance Scale.
Total hip and femoral neck BMD in females were 3.1–3.9% higher among those with the highest yogurt intakes (n = 970) compared to the lowest (n = 1109; P < 0.05) as were the TUG scores (−6.7%; P = 0.013). In males, tartrate-resistant acid phosphatase (TRAP 5b) concentrations were significantly lower in those with the highest yogurt intakes (−9.5%; P < 0.0001). In females, yogurt intake was a significant positive predictor of BMD at all regions. Each unit increase in yogurt intake in females was associated with a 31% lower risk of osteopenia (OR 0.69; 95% CI 0.49–0.96; P = 0.032) and a 39% lower risk of osteoporosis (OR 0.61; 95% CI 0.42–0.89; P = 0.012) and in males, a 52% lower risk of osteoporosis (OR 0.48; 95% CI 0.24–0.96; P = 0.038).
In this cohort, higher yogurt intake was associated with increased BMD and physical function scores. These results suggest that improving yogurt intakes could be a valuable public health strategy for maintaining bone health in older adults.
KeywordsAging BMD Frailty Physical function Yogurt
The TUDA study was funded by the Irish Department of Agriculture, Food, and the Marine through the grants 07FHRIUCD1 (“JINGO” 2007–2013) and 13F407 (“JINGO–JPI”/“ENPADASI” 2014–2016) and from the Northern Ireland Department for Employment and Learning under its “Strengthening the all-Ireland Research Base” initiative. Funding for this study was also provided from The National Dairy Council Ireland. The funding organizations had no role in the design and conduct, collection, management, analysis, and interpretation of the data or in the preparation, review, or approval of this manuscript. The authors also acknowledge Drs Martin Healy, Adrian McCann, and Liadhan McAnena for bone biochemical analysis.
Compliance with ethical standards
Ethical approval was granted by the relevant authorities in each jurisdiction: the Research Ethics Committee of St. James’s Hospital and The Adelaide and Meath Hospital, Dublin, and the Office for Research Ethics Committees Northern Ireland (ORECNI; reference 08/NI/RO3113) with corresponding approvals from the Northern and Western Health and Social Care Trusts, Northern Ireland.
Conflict of interest
- 5.Hernlund E, Svedbom A, Ivergård M, Compston J, Cooper C, Stenmark J, McCloskey EV, Jönsson B, Kanis JA (2013) Osteoporosis in the European Union: medical management, epidemiology and economic burden. Arch Osteoporos 8(1–2):1–15Google Scholar
- 16.Dietary guidelines for Americans (2005) Dietary guidelines advisory committee report. 6. U.S. Department of Health and Human Services and U.S. Department of Agriculture, U.S. Government; WashingtonGoogle Scholar
- 17.Sahni S, Tucker KL, Kiel DP, Quach L, Casey VA, Hannan MT (2013) Milk and yogurt consumption are linked with higher bone mineral density but not with hip fracture: the Framingham Offspring Study. Arch Osteoporos 8(1–2):1–9Google Scholar
- 21.Laird E, Casey MC, Ward M et al (2016) Dairy intakes in older Irish adults and effects on vitamin micronutrient status: Data from the TUDA study. J Nutr Health Aging. In PressGoogle Scholar
- 22.Irish Universities Nutrition Alliance (2013) The Irish food portion sizes database (1st edition) 2013Google Scholar
- 23.World Health Organization (1992) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: report of a WHO study group (meeting held in Rome from 22 to 25 June 1992)Google Scholar
- 26.Hochberg MC, Greenspan S, Wasnich RD, Miller P, Thompson DE, Ross PD (2002) Changes in bone density and turnover explain the reductions in incidence of non-vertebral fractures that occur during treatment with anti-resorptive agents. J Clin Endocrinol Metab 87(4):1586–1592PubMedCrossRefGoogle Scholar
- 28.Bonjour JP, Benoit V, Payen F, Kraenzlin M (2013) Consumption of yogurts fortified in vitamin D and calcium reduces serum parathyroid hormone and markers of bone resorption: a double-blind randomized controlled trial in institutionalized elderly women. J Clin Endocrinol Metab 98(7):2915–2921PubMedCrossRefGoogle Scholar
- 36.Parvaneh K, Jamaluddin R, Karimi G, Erfani R (2014) Effect of probiotics supplementation on bone mineral content and bone mass density. ScientificWorldJournal 22:595962Google Scholar
- 37.Parvaneh K, Ebrahimi M, Sabran MR, Karimi G, Hwei AN, Abdul-Majeed S, Ahmad Z, Ibrahim Z, Jamaluddin R (2015) Probiotics (Bifidobacterium longum) increase bone mass density and upregulate Sparc and Bmp-2 genes in rats with bone loss resulting from ovariectomy. Biomed Res Int. doi: 10.1155/2015/897639 PubMedPubMedCentralGoogle Scholar
- 47.United States Department of Agriculture (USDA) (2016) National Nutrient Database for Standard Reference Release 8. Yogurt, fruit, low fat, 9 grams protein per 8 ounce, Basic Report 01120. Accessed 4th July 2016Google Scholar
- 48.United States Department of Agriculture (USDA) (2016) National Nutrient Database for Standard Reference Release 8. Yogurt, Greek, plain, low fat, Basic Report 01287. Accessed 4th July 2016Google Scholar
- 50.Rozenberg S, Body JJ, Bruyère O et al (2016) Effects of dairy products consumption on health: benefits and beliefs—a commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases. Calcif Tissue Int 98(1):1–7PubMedCrossRefGoogle Scholar