Skip to main content
SpringerLink
Log in

Full 24-month treatment course with daily teriparatide: a mechanistic insight

  • Letter
  • Published:
Osteoporosis International Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Lindsay R, Krege JH, Martin F, Jin L, Stepan JJ (2016) Teriparatide for osteoporosis: importance of the full course. Osteoporos Int. doi:10.1007/s00198-016-3534-6

    PubMed  Google Scholar 

  2. Beall DP, Feldman RG, Gordon ML, Gruber BL, Lane JM, Valenzuela G, Yim D, Alam J, Krege JH, Krohn K (2016) Patients with prior vertebral or hip fractures treated with teriparatide in the Direct Assessment of Nonvertebral Fractures in Community Experience (DANCE) observational study. Osteoporos Int 27:1191–1198

    Article  CAS  PubMed  Google Scholar 

  3. McCurry J (2015) Japan will be model for future super-ageing societies. Lancet 386:1523

    Article  PubMed  Google Scholar 

  4. Niimi R, Kono T, Nishihara A, Hasegawa M, Matsumine A, Kono T, Sudo A (2015) Analysis of daily teriparatide treatment for osteoporosis in men. Osteoporos Int 26:1303–1309

    Article  CAS  PubMed  Google Scholar 

  5. Niimi R, Kono T, Nishihara A, Hasegawa M, Matsumine A, Kono T, Sudo A (2016) Usefulness of daily teriparatide treatment in elderly patients over 80 years of age. Osteoporos Int 27:1869–1874. doi:10.1007/s00198-015-3479-1

    Article  CAS  PubMed  Google Scholar 

  6. Silva BC, Bilezikian JP (2015) Parathyroid hormone: anabolic and catabolic actions on the skeleton. Curr Opin Pharmacol 22:41–50

    Article  CAS  PubMed  Google Scholar 

  7. Sugiyama T, Torio T, Sato T, Matsumoto M, Kim YT, Oda H (2015) Improvement of skeletal fragility by teriparatide in adult osteoporosis patients: a novel mechanostat-based hypothesis for bone quality. Front Endocrinol 6:6

    Google Scholar 

  8. Pazianas M (2015) Anabolic effects of PTH and the ‘anabolic window’. Trends Endocrinol Metab 26:111–113

    Article  CAS  PubMed  Google Scholar 

  9. Seeman E, Martin TJ (2015) Co-administration of antiresorptive and anabolic agents: a missed opportunity. J Bone Miner Res 30:753–764

    Article  CAS  PubMed  Google Scholar 

  10. Eriksen EF, Brown JP (2016) Concurrent administration of PTH and antiresorptives: additive effects or DXA cosmetics. Bone 86:139–142

    Article  CAS  PubMed  Google Scholar 

  11. Sugiyama T, Tanaka H, Taguchi T (2004) Glucocorticoids and bone mineral content in the childhood nephrotic syndrome. N Engl J Med 351:2655–2656

    Article  CAS  PubMed  Google Scholar 

  12. Sugiyama T, Saxon LK, Zaman G, Moustafa A, Sunters A, Price JS, Lanyon LE (2008) Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1–34) on trabecular and cortical bone in mice. Bone 43:238–248

    Article  CAS  PubMed  Google Scholar 

  13. Erben RG (2015) Hypothesis: coupling between resorption and formation in cancellous bone remodeling is a mechanically controlled event. Front Endocrinol 6:82

    Article  Google Scholar 

  14. Sugiyama T, Kim YT, Oda H (2016) Strontium ranelate in the treatment of osteoporosis: a possible mechanism. J Clin Endocrinol Metab. doi:10.1210/jc.2016-1479

    Google Scholar 

  15. Leder BZ, Tsai JN, Uihlein AV, Wallance PM, Lee H, Neer RM, Burnett-Bowie SA (2015) Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-switch study): extension of a randomised controlled trial. Lancet 386:1147–1155

    Article  CAS  PubMed  Google Scholar 

  16. Dempster DW, Roschger P, Misof BM, Zhou H, Paschalis EP, Alam J, Ruff VA, Klaushofer K, Taylor KA (2016) Differential effects of teriparatide and zoledronic acid on bone mineralization density distribution at 6 and 24 months in the SHOTZ study. J Bone Miner Res. doi:10.1002/jbmr.2825

    Google Scholar 

  17. Sugiyama T, Kim YT, Oda H (2016) A possible mechanism of denosumab treatment for fracture prevention. J Clin Endocrinol Metab 101:L15–L16

    Article  PubMed  Google Scholar 

  18. Dempster DW, Zhou H, Recker RR, Brown JP, Bolognese MA, Recknor CP, Kendler DL, Lewiecki EM, Hanley DA, Rao SD, Miller PD, Woodson GC III, Lindsay R, Binkley N, Alam J, Ruff VA, Gallagher ER, Taylor KA (2016) A longitudinal study of skeletal histomorphometry at 6 and 24 months across four bone envelopes in postmenopausal women with osteoporosis receiving teriparatide or zoledronic acid in the SHOTZ trial. J Bone Miner Res. doi:10.1002/jbmr.2804

    Google Scholar 

  19. Whitmarsh T, Treece GM, Gee AH, Poole KE (2015) The effects on the femoral cortex of a 24 months treatment compared to an 18 months treatment with teriparatide: a multi-trial retrospective analysis. PLoS One 11:e0147722

    Article  Google Scholar 

  20. Cosman F, Dempster DW, Nieves JW, Zhou H, Zion M, Roimisher C, Houle Y, Lindsay R, Bostrom M (2016) Effect of teriparatide on bone formation in the human femoral neck. J Clin Endocrinol Metab. doi:10.1210/jc.2015-3698

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Saitama Medical University, 38 Morohongo, Moroyama, Saitama, 350-0495, Japan

    T. Sugiyama, Y. Kono, K. Sekiguchi, Y. T. Kim & H. Oda

Authors
  1. T. Sugiyama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Y. Kono
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. K. Sekiguchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Y. T. Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. Oda
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to T. Sugiyama.

Ethics declarations

Conflicts of interest

None.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sugiyama, T., Kono, Y., Sekiguchi, K. et al. Full 24-month treatment course with daily teriparatide: a mechanistic insight. Osteoporos Int 27, 2635–2636 (2016). https://doi.org/10.1007/s00198-016-3630-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00198-016-3630-7

Keywords

Search

Navigation