Skip to main content

Advertisement

Log in

Bone mineral densities in patients with developmental dysplasia of the hip

  • Original Article
  • Published:
Osteoporosis International Aims and scope Submit manuscript

Abstract

Summary

Bone mineral density (BMD) of the lumbar spine, ultradistal radius, and calcaneus were significantly higher in the developmental dysplasia of the hip (DDH) patients than in the controls. Therefore, our data suggest that BMDs at different skeletal sites are greater in patients with DDH than in healthy women.

Introduction

DDH has been acknowledged as a potentially preosteoarthritic condition that results in the development of hip osteoarthritis. Patients with DDH have been reported to have abnormal morphology of the pelvis and spine. Additional research, including that of bone quality, needs to be conducted to elucidate the pathogenetic mechanism of this disease. We therefore sought to determine whether BMD differs between healthy women and women with DDH.

Methods

We measured BMD in 40 women who were scheduled to undergo pelvic osteotomy for DDH (average age, 45.3 years) and in 31 healthy women used as age-matched controls (average age, 47.5 years). BMDs of the lumbar spine, radius, and calcaneus were measured.

Results

BMDs of the lumbar spine, ultradistal radius, and calcaneus were significantly higher in the DDH patients than in the controls.

Conclusions

Therefore, our data suggest that BMDs at different skeletal sites are greater in patients with DDH than in healthy women.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Maggi S, Kelsey JL, Litvak J, Heyse SP (1991) Incidence of hip fractures in the elderly: a cross-national analysis. Osteoporos Int 1:232–241

    Article  CAS  PubMed  Google Scholar 

  2. Cimmino MA, Parodi M (2005) Risk factors for osteoarthritis. Semin Arthritis Rheum 34:29–34

    Article  PubMed  Google Scholar 

  3. Stewart A, Black AJ (2000) Bone mineral density in osteoarthritis. Curr Opin Rheumatol 12:464–467

    Article  CAS  PubMed  Google Scholar 

  4. Dequeker J, Aerssens J, Luyten FP (2003) Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res 15:426–439

    PubMed  Google Scholar 

  5. Nevitt MC, Lane NE, Scott JC, Hochberg MC, Pressman AR, Genant HK, Cummings SR (1995) Radiographic osteoarthritis of the hip and bone mineral density. The Study of Osteoporotic Fractures Research Group. Arthritis Rheum 38:907–916

    Article  CAS  PubMed  Google Scholar 

  6. Burger H, van Daele PL, Odding E, Valkenburg HA, Hofman A, Grobbee DE, Schutte HE, Birkenhager JC, Pols HA (1996) Association of radiographically evident osteoarthritis with higher bone mineral density and increased bone loss with age. The Rotterdam Study. Arthritis Rheum 39:81–86

    Article  CAS  PubMed  Google Scholar 

  7. Gotfredsen A, Riis BJ, Christiansen C, Rodbro P (1990) Does a single local absorptiometric bone measurement indicate the overall skeletal status? Implications for osteoporosis and osteoarthritis of the hip. Clin Rheumatol 9:193–203

    Article  CAS  PubMed  Google Scholar 

  8. Nakamura S, Ninomiya S, Nakamura T (1989) Primary osteoarthritis of the hip joint in Japan. Clin Orthop Relat Res 241:190–196

    PubMed  Google Scholar 

  9. Funayama K, Koike M, Miyagishima J, Wakamatsu E (1984) Hip-shelf operation (nodified Spitzy) for young adult women. In: Ueno R, Akamatsu N, Itami Y, Tagawa H, Yoshino S (eds) The hip: clinical studies and basic research. Elsevier Science, Amsterdam, pp 105–109

    Google Scholar 

  10. Kojima S, Kobayashi S, Saito N, Nawata M, Horiuchi H, Takaoka K (2001) Morphological characteristics of the bony birth canal in patients with developmental dysplasia of the hip (DDH): investigation by three-dimensional CT. J Orthop Sci 6:217–222

    Article  CAS  PubMed  Google Scholar 

  11. Ucar DH, Omeroglu H, Eren A, Inan M, Baktir A, Aksoy MC, Omeroglu S (2003) Occult spinal dysraphism and its association with hip dysplasia in females. Int Orthop 27:70–72

    CAS  PubMed  Google Scholar 

  12. Crowe JF, Mani VJ, Ranawat CS (1979) Total hip replacement in congenital dislocation and dysplasia of the hip. J Bone Joint Surg Am 61:15–23

    CAS  PubMed  Google Scholar 

  13. Wiberg G (1939) Studies on dysplastic acetabula and congenital subluxation of the hip joint. With special reference to the complication of osteoarthritis. Acta Chir Scand 58:28–38

    Google Scholar 

  14. Heyman CH, Herndon CH (1950) Legg-Perthes disease. A method for the measurement of the rentogenographic result. J Bone Joint Surg 32-A:767–768

    Google Scholar 

  15. Sharp IK (1961) Acetabular dysplasia: the acetabular angle. J Bone Joint Surg Br 43:268–272

    Google Scholar 

  16. Massie WK, Howorth MB (1950) Congenital dislocation of the hip. Part I. Method of grading results. J Bone Joint Surg Am 32-A:519–531

    CAS  PubMed  Google Scholar 

  17. Jacobsen S, Sonne-Holm S, Soballe K, Gebuhr P, Lund B (2005) Hip dysplasia and osteoarthrosis: a survey of 4151 subjects from the Osteoarthrosis Substudy of the Copenhagen City Heart Study. Acta Orthop 76:149–158

    Article  PubMed  Google Scholar 

  18. Nakamura S, Ninomiya S, Takatori Y, Morimoto S, Umeyama T (1998) Long-term outcome of rotational acetabular osteotomy: 145 hips followed for 10–23 years. Acta Orthop Scand 69:259–265

    Article  CAS  PubMed  Google Scholar 

  19. Merle d’Aubigne R, Postel M (1954) Functional results of hip arthroplasty with acrylic prosthesis. J Bone Joint Surg Am 36-A:451–475

    Google Scholar 

  20. Ito M, Nakamura T, Tsurusaki K, Uetani M, Hayashi K (1999) Effects of menopause on age-dependent bone loss in the axial and appendicular skeletons in healthy Japanese women. Osteoporos Int 10:377–383

    Article  CAS  PubMed  Google Scholar 

  21. Jordan GR, Loveridge N, Bell KL, Power J, Dickson GR, Vedi S, Rushton N, Clarke MT, Reeve J (2003) Increased femoral neck cancellous bone and connectivity in coxarthrosis (hip osteoarthritis). Bone 32:86–95

    Article  CAS  PubMed  Google Scholar 

  22. Antoniades L, MacGregor AJ, Matson M, Spector TD (2000) A co-twin control study of the relationship between hip osteoarthritis and bone mineral density. Arthritis Rheum 43:1450–1455

    Article  CAS  PubMed  Google Scholar 

  23. Cushnaghan J, Dieppe P (1991) Study of 500 patients with limb joint osteoarthritis. I. Analysis by age, sex, and distribution of symptomatic joint sites. Ann Rheum Dis 50:8–13

    Article  CAS  PubMed  Google Scholar 

  24. Stewart A, Black A, Robins SP, Reid DM (1999) Bone density and bone turnover in patients with osteoarthritis and osteoporosis. J Rheumatol 26:622–626

    CAS  PubMed  Google Scholar 

  25. Okano K, Takaki M, Okazaki N, Shindo H (2008) Bilateral incidence and severity of acetabular dysplasia of the hip. J Orthop Sci 13:401–404

    Article  PubMed  Google Scholar 

  26. Obermayer-Pietsch BM, Walter D, Kotschan S, Freigassner-Pritz M, Windhager R, Leb G (2000) Congenital hip dysplasia and bone mineral density of the hip—a new risk factor for osteoporotic fracture? J Bone Miner Res 15:1678–1682

    Article  CAS  PubMed  Google Scholar 

  27. Yoshimura N, Morioka S, Kasamatsu T, Hashimoto T, Kinoshita H, Okayasu T, Cooper C (1994) Distribution of indices of hip joint space classified by sex and age in general inhabitants of Japan. Japanese Society for Bone Morphometry 4:107–112

    Google Scholar 

  28. Goodyear SR, Gibson IR, Skakle JM, Wells RP, Aspden RM (2009) A comparison of cortical and trabecular bone from C57 Black 6 mice using Raman spectroscopy. Bone 44:899–907

    Article  PubMed  Google Scholar 

  29. Aspden RM (2008) Osteoarthritis: a problem of growth not decay? Rheumatology (Oxford) 47:1452–1460

    Article  CAS  Google Scholar 

Download references

Conflicts of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. Okano.

Additional information

No benefits in any form have been received or will be received from a commercial party related directly to the subject of this article.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Okano, K., Ito, M., Aoyagi, K. et al. Bone mineral densities in patients with developmental dysplasia of the hip. Osteoporos Int 22, 201–205 (2011). https://doi.org/10.1007/s00198-010-1227-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00198-010-1227-0

Keywords

Navigation