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Ungewöhnliche Komplikation eines hepatozellulären Karzinoms

Unusual complication of a hepatocellular carcinoma

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Zusammenfassung

Gastrointestinale Blutungen durch direkten Tumoreinbruch eines hepatozellulären Karzinoms (HCC) in das Duodenum sind sehr selten. In der nachfolgenden Kasuistik wird über eine 75-jährige Frau berichtet, bei der die Sektion eine solche, tödlich verlaufende, intestinale Blutung als ungewöhnliche Komplikation eines HCC ergab. Insbesondere werden immunhistochemische Untersuchungsmethoden, wie das HepPar1-Antigen und das D11-Antigen zur Markierung hepatozellulärer Karzinome sowie der Proliferationsmarker Ki67-Antigen (MIB1), berücksichtigt.

Abstract

Gastrointestinal bleeding from a hepatocellular carcinoma invading the duodenum is vary rare. Here we report on the case of a 75-year-old woman, where the autopsy revealed such a fatal bleeding as an unusual complication of a hepatocellular carcinoma. Especially immunohistochemical methods, such as HepPar1 antigen and D11 antigen as markers for identifying a hepatocellular carcinoma and Ki67 Antigen (MIB1) as a proliferation marker are discussed.

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Authors and Affiliations

  1. Institut für Rechtsmedizin, Universitätsklinikum, Hamburg-Eppendorf

    U. Zimmermann & F. Schulz

  2. Institut für Pathologie, Universitätsklinikum, Hamburg-Eppendorf

    H.-J. Schäfer

  3. Wartburgstraße 25 A, 10825, Berlin

    U. Zimmermann

Authors
  1. U. Zimmermann
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  2. F. Schulz
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  3. H.-J. Schäfer
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Correspondence to U. Zimmermann.

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Zimmermann, U., Schulz, F. & Schäfer, HJ. Ungewöhnliche Komplikation eines hepatozellulären Karzinoms. Rechtsmedizin 14, 467–472 (2004). https://doi.org/10.1007/s00194-004-0295-x

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  • DOI: https://doi.org/10.1007/s00194-004-0295-x

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