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Association of Urinary Incontinence with Sensory-Motor Performance in Women with Multiple Sclerosis

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Abstract

Introduction and Hypothesis

The relationship between somatosensory and motor components of urinary incontinence in individuals with MS has not been extensively addressed. The study was aimed at investigating the association of urinary incontinence severity with motor and sensory performance in women with multiple sclerosis (MS).

Methods

A cross-sectional single-center prospective study was conducted in 337 women with MS. The severity of MS symptoms was assessed using the SymptoMScreen questionnaire. The urinary incontinence status of the participants was evaluated using the Urinary Incontinence Inventory (UDI-6) and the Incontinence Impact Questionnaire (IIQ-7). Physical performance was considered with the Timed Up and Go (TUG) test and the 5-Times Sit-to-Stand (5TSTS) test. In addition, the sensory performance of the individuals with MS was queried using the Somatosensory Amplification Scale (SSAS) and Sensory Sensitivity Scale (SeSS).

Results

The UDI-6 (r=0.685, p<0.05) and IIQ-7 (r=0.759, p<0.05) correlated highly with SymptoMScreen. Among the physical performance measures, TUG (r=0.012, p<0.05) and 5TSTS (r=0.096, p<0.05) were weakly associated with UDI-6, but not statistically significantly. Similarly, there was a low correlation between IIQ-7 and TUG (r=−0.005, p<0.05) and 5TSTS (r=0.068, p<0.05). UDI-6 (0.360, p<0.05) and IIQ-7 (0.378, p<0.05) correlated moderately with SASS. On the other hand, SeSS had a low correlation coefficient with UDI-6 (0.305, p<0.05) and IIQ-7 (0.272, p<0.05).

Conclusions

The results revealed that sensory performance was more associated with urinary incontinence in women with MS than physical performance. The urinary incontinence severity was also related to MS symptoms (bladder control, walking, spasticity, stiffness cognitive function). Future studies should consider the potential impact of sensory performance on urinary incontinence and focus on explaining the mechanism behind this relationship.

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Data Availability

All data generated or analyzed during this study are included in this published article.

Abbreviations

CNS:

Central nervous system

IIQ-7:

Incontinence Impact Questionnaire

LUTS:

Lower urinary tract symptom

MS:

Multiple sclerosis

SD:

Standard deviation

SeSS:

Sensory Sensitivity Scale

SSAS:

Somatosensory Amplification Scale

5TSTS:

Five Times Sit to Stand

TUG:

Timed Up and Go

UDI-6:

Urinary Incontinence Inventory

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Authors and Affiliations

Authors

Contributions

F.Ö. and Z.S.: data analysis and interpretation; F.Ö. and M.Ö.: manuscript writing; N.Y. and E.E.: data collection; all authors: project development and manuscript editing.

Corresponding author

Correspondence to Fatih Özden.

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Conflicts of Interest

The authors report no conflicts of interest and certify that no funding has been received for this study and/or preparation of this manuscript.

Ethical Approval

The study was carried out in accordance with the ethical principles and the Declaration of Helsinki. The study protocol was approved by the ethics committee of Ege University (No: 23-11.2T/21, Date: 01.09.2023).

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Informed consent of the patients was obtained.

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Handling Editor: Tony Bazi

Editor in Chief: Maria A. Bortolini

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Özden, F., Özkeskin, M., Sarı, Z. et al. Association of Urinary Incontinence with Sensory-Motor Performance in Women with Multiple Sclerosis. Int Urogynecol J (2024). https://doi.org/10.1007/s00192-024-05854-9

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