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Mid-term results of the Remeex® readjustable sling for female complex stress urinary incontinence and sonographic hypomobile urethra

Abstract

Introduction and hypothesis

We aimed to evaluate the results of a readjustable sling (Remeex® system) among a selected group of women with complex stress urinary incontinence (SUI) with sonographic hypomobile urethra and assessing failure-related risk factors.

Methods

Observational, longitudinal, prospective cohort study, including patients who underwent surgery with the Remeex® system. The primary outcome was a binary outcome in change of one level or more of the severity of urinary incontinence symptoms according to the intervals of the Incontinence Questionnaire-Short Form (ICIQ-UI-SF) score (mild, moderate, severe and very severe). Secondary outcomes were postsurgical complications, absolute ICIQ-UI-SF, 24-h pad weight test (24-h PT), urodynamic SUI and Patient Global Impression of Improvement (PGI-I) score to evaluate subjective success.

Results

Among 120 women included, after surgery we found a 70% subjective success rate, a 76.7% decrease of urinary incontinence severity and a mean reduction of the 24-h PT of 109.6 ± 291.4 g. Women with post-surgical decreased severity of incontinence had lower mean body mass index (BMI) and 24-h PT than those without incontinence severity changes with statistically significant differences (p = 0.028 and p = 0.027, respectively). A logistic regression model demonstrated that a 1-point increase of BMI increased the risk of persistence of incontinence severity after surgery by 19% (OR = 1.19; 95% CI: 1.01–1.41; p = 0.040), and an increase of 10 g in the pre-surgical 24-h PT represented a 3% rise of the aforementioned risk (OR = 1.03; 95% CI: 1.01–1.06; p = 0.034).

Conclusions

In patients with complex SUI and sonographic hypomobile urethra, use of a readjustable sling (Remeex® system) led to improvement of SUI. Patients with a greater BMI and pre-surgical 24-h PT showed worse results after surgery.

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Affiliations

Authors

Contributions

C. Ros: project development, data collection, data analysis, manuscript writing, manuscript editing.

S. Escura: project development, data collection, data analysis, manuscript writing, manuscript editing.

S. Anglès-Acedo: manuscript editing.

M. Larroya: data collection.

E. Bataller: surgery.

LL. Amat: surgery, data collection.

E. Sánchez: data analysis.

M. Espuña-Pons: project development, manuscript editing.

F. Carmona: manuscript editing.

Corresponding author

Correspondence to Cristina Ros.

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Ros, C., Escura, S., Anglès-Acedo, S. et al. Mid-term results of the Remeex® readjustable sling for female complex stress urinary incontinence and sonographic hypomobile urethra. Int Urogynecol J (2021). https://doi.org/10.1007/s00192-021-04972-y

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Keywords

  • Recurrent stress urinary incontinence
  • Hypomobile urethra
  • Ultrasound
  • Mid-urethral sling
  • Readjustable sling