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The prevalence of frailty and post-treatment outcomes in elderly women with pelvic floor disorders

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Abstract

Introduction and hypothesis

Women seeking treatment for pelvic floor disorders (PFD) may have a high prevalence of frailty, which could potentially impact the risks of treatment. The present study was aimed to assess the prevalence of frailty in patients with PFD and additionally to compare post-treatment complications between frail and non-frail patients.

Methods

This is a prospective observational study conducted in a single secondary referral centre for PFD. Women with PFD and aged ≥ 65 years were eligible for inclusion. Frailty was classified using a validated screening tool, the Groningen Frailty Indicator (GFI). The primary outcome was to determine the prevalence of frailty in elderly women with symptoms of pelvic floor disorders. Secondary outcomes were clinical outcomes after treatment between frail and non-frail patients.

Results

A total of 263 women were included. The prevalence of frailty was 54.4% (143 women, 95% CI 48.1–60.5) in the studied group of patients. Frail patients had more comorbidities and used more medication compared to non-frail patients. Non-frail patients were more often surgically treated than frail patients. No differences were found in the incidence of postoperative complications.

Conclusions

Our study shows a high prevalence of frailty in elderly women with symptoms of PFD. Further research is required to investigate whether these frail patients face an increased risk of complications and poor clinical outcomes after treatment for PFD.

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Abbreviations

PFD:

Pelvic floor dysfunction

GFI:

Groningen Frailty Indicator

References

  1. Erekson EA, Fried TR, Martin DK, Rutherford TJ, Strohbehn K, Bynum JP. Frailty, cognitive impairment, and functional disability in older women with female pelvic floor dysfunction. Int Urogynecol J. 2015;26(6):823–30. https://doi.org/10.1007/s00192-014-2596-2.

    Article  PubMed  Google Scholar 

  2. Gibson W, Athanasopoulos A, Goldman H, Madersbacher H, Newman D, Spinks J, et al. Are we shortchanging frail older people when it comes to the pharmacological treatment of urgency urinary incontinence? Int J Clin Pract. 2014;68:1165–73. https://doi.org/10.1111/ijcp.12447.

    Article  CAS  PubMed  Google Scholar 

  3. Hewitt J, Long S, Carter B, Bach S, McCarthy K, Clegg A. The prevalence of frailty and its association with clinical outcomes in general surgery: a systematic review and meta-analysis. Age Ageing. 2018;47(6):793–800. https://doi.org/10.1093/ageing/afy110.

    Article  PubMed  Google Scholar 

  4. Hewitt J, Moug SJ, Middleton M, Chakrabarti M, Stechman MJ, McCarthy K. Prevalence of frailty and its association with mortality in general surgery. Am J Surg. 2015;209:254–9. https://doi.org/10.1016/j.amjsurg.2014.05.022.

    Article  PubMed  Google Scholar 

  5. Goeteyn J, Evans LA, De Cleyn S, Fauconnier S, Damen C, Hewitt J, et al. Frailty as a predictor of mortality in the elderly emergency general surgery patient. Acta Chir Belg. 2017;117:370–5. https://doi.org/10.1080/00015458.2017.1337339.

    Article  PubMed  Google Scholar 

  6. Anayi AC, Orkaby AR, Sakthivel D, Endo Y, Varon D, Roh D, et al. Impact of frailty on outcomes in surgical patients: a systematic review and meta-analysis. Am J Surg. 2019;218(2):393–400. https://doi.org/10.1016/j.amjsurg.2018.11.020.

    Article  Google Scholar 

  7. Robinson TN, Wallace JI, Wu DS, Wiktor A, Pointer LF, Pfister SM, et al. Accumulated frailty characteristics predict postoperative discharge institutionalisation in the geriatric patient. J Am Coll Surg. 2011;213(1):37–44. https://doi.org/10.1016/j.jamcollsurg.2011.01.056.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Robinson TN, Raeburn CD, Tran ZV, Angles EM, Brenner LA, Moss M. Postoperative delirium in the elderly: risk factors and outcomes. Ann Surg. 2009;249(1):173–8. https://doi.org/10.1097/SLA.0b013e31818e4776.

    Article  PubMed  Google Scholar 

  9. Erekson EA, Yip SO, Ciarleglio MM, Fried TR. Postoperative complications after gynecologic surgery. Obstet Gynecol. 2011;118(4):785–93. https://doi.org/10.1097/AOG.0b013e31822dac5d.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Smith FJ, Holman CD, Moorin RE, Tsokos N. Lifetime risk of undergoing surgery for pelvic organ prolapse. Obstet Gynecol. 2010;116(5):1096–100. https://doi.org/10.1097/AOG.0b013e3181f73729.

    Article  PubMed  Google Scholar 

  11. Samuelsson E, Odeberg J, Stenzelius K, Molander U, Hammarström M, Franzen K, et al. Effect of pharmacological treatment for urinary incontinence in the elderly and frail elderly: a systematic review. Geriatr Gerontol Int. 2015;15:521–34. https://doi.org/10.1111/ggi.12451.

    Article  PubMed  Google Scholar 

  12. Zeno A, Alvarez P, Yazdany T. A systematic review of frailty assessments in women with pelvic floor disorders: are we following the American College of Surgeons National Surgical Quality Improvement Program/American Geriatric Society guidelines? Female Pelvic Med Reconstr Surg. 2018;24(2):135–41. https://doi.org/10.1097/SPV.0000000000000508.

    Article  PubMed  Google Scholar 

  13. Shinnick JK, Raker CA, Sung V. Provider miscategorisation of frailty in an outpatient urogynecologic population. Int Urogynecol J. 2020;31(8):1529–35. https://doi.org/10.1007/s00192-019-04095-5.

    Article  PubMed  Google Scholar 

  14. Schuurmans H, Steverink N, Lindenberg S, Frieswijk N, Slaets JP. Old or frail: what tells us more? J Gerontol A Biol Sci Med Sci. 2004;59(9):M962–5. https://doi.org/10.1093/gerona/59.9.m962.

    Article  PubMed  Google Scholar 

  15. Steverink N, Slaets JPJ, Schuurmans H, van Lis M. Measuring frailty: development and testing of the Groningen frailty indicator (GFI). Gerontologist. 2001;41:236–7.

    Google Scholar 

  16. Drubbel I, Bleijenberg N, Kranenburg G, Eijkemans RJ, Schuurmans MJ, de Wit NJ, et al. Identifying frailty: do the frailty index and Groningen frailty Indicator cover different clinical perspectives? A cross-sectional study. BMC Fam Pract. 2013;14:64. https://doi.org/10.1186/1471-2296-14-64.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Berardelli M, De Rango F, Morelli M, Corsonello A, Mazzei B, Mari V, et al. Urinary incontinence in the elderly and in the oldest old: correlation with frailty and mortality. Rejuvenation Res. 2013;16(3):206–11. https://doi.org/10.1089/rej.2013.1417.

    Article  PubMed  Google Scholar 

  18. Chen X, Mao G, Leng SX. Frailty syndrome: an overview. Clin Interv Aging. 2014;9:433–41. https://doi.org/10.2147/CIA.S45300.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Chong E, Chan M, Lim WS, Ding YY. Frailty predicts incident urinary incontinence among hospitalized older adults-a 1-year prospective cohort study. J Am Med Dir Assoc. 2018;9(5):422–7. https://doi.org/10.1016/j.jamda.2017.12.103.

    Article  Google Scholar 

  20. Vetrano DL, Palmer KM, Galluzzo L, Giampaoli S, Marengoni A, Bernabei R, et al. Hypertension and frailty: a systematic review and meta-analysis. BMJ Open. 2018;8(12):e024406. https://doi.org/10.1136/bmjopen-2018-024406.

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

The authors thank Sara Baart and Joost van Rosmalen for their supporting roles in the data analysis and Riëlla Bambelt for managing data.

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Authors and Affiliations

Authors

Contributions

K de Jong: Data analysis, Data management, Manuscript writing and editing.

MY van der Vlist: Project development, Protocol writing, Data collection, Manuscript editing.

DMJ Oom: Project development, Protocol editing, Manuscript editing.

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Correspondence to Kelly de Jong.

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de Jong, K., van der Vlist, M.Y. & Oom, D.M.J. The prevalence of frailty and post-treatment outcomes in elderly women with pelvic floor disorders. Int Urogynecol J 32, 3001–3006 (2021). https://doi.org/10.1007/s00192-021-04682-5

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  • DOI: https://doi.org/10.1007/s00192-021-04682-5

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