Abstract
Introduction and hypothesis
Recurrent urinary tract infections (rUTIs) affect up to 44% of women; evidenced-based guidelines regarding the contributory role of a pelvic examination in these women are lacking. We hypothesize that routine pelvic examination has a limited role in evaluation and management of women with rUTI when appropriate symptoms-based screening is performed and normal post-void residual volume (PVR) is confirmed.
Methods
We performed a retrospective chart review of women ages 18–85 years presenting to Wake Forest Pelvic Health Center with two culture-proven UTIs in 6 months or three UTIs in 12 months with a documented pelvic examination. Pregnant women were excluded. Data extraction included demographics, medical history, screening assessment of vaginal bulge symptoms, urine culture results, imaging, physical/pelvic examination findings, PVR, treatment recommendations and outcomes within 1 year of initial assessment. Descriptive statistics and Fisher’s exact test were performed.
Results
Of 160 charts screened, 91 met the inclusion criteria. Nineteen (21%) had symptoms of vaginal bulge, and 14 (17%) had PVR > 100 ml. Pelvic examination provided new/contributory information in eight (8.8%) of women. The negative predictive value of absence of bulge symptoms and normal PVR was 89%. Within 1 year, 41 (46%) reported symptom resolution with rUTI treatment with no difference between those with or without a contributory pelvic examination (p value = 0.64).
Conclusions
In women with rUTI who report absence of vaginal bulge symptoms and have a PVR < 100 ml, a pelvic examination provides contributory information in < 10% of women and did not change treatment outcomes.
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O Hostetter: Project development, data collection, manuscript writing and editing.
K Hemal: Project development, data collection, data analysis.
K Hines: Data collection, manuscript editing.
C Matthews: Protocol and project development, data analysis, manuscript writing and editing.
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Dr. Matthews serves as an expert witness for Johnson& Johnson and has received grant support and consultant fees from Boston Scientific.
Hostetter O, MD, Hemal K, BS, and Hines K, MD, have no conflicts of interest to report.
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Hostetter, O., Hemal, K., Hines, K.N. et al. Is a pelvic examination contributory in the initial evaluation of women with recurrent urinary tract infections?. Int Urogynecol J 31, 1209–1214 (2020). https://doi.org/10.1007/s00192-019-04198-z
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DOI: https://doi.org/10.1007/s00192-019-04198-z