Risk factors for anatomic pelvic organ prolapse at 6 weeks postpartum: a prospective observational study

  • Cathrine Reimers
  • Franziska Siafarikas
  • Jette Stær-Jensen
  • Milada Cvancarova Småstuen
  • Kari Bø
  • Marie Ellström Engh
Original Article
  • 18 Downloads

Abstract

Introduction and hypothesis

The objective was to identify risk factors for postpartum anatomic pelvic organ prolapse (aPOP) by comparing women with and without aPOP at 6 weeks postpartum with regard to pelvic floor measurements antepartum and obstetrical characteristics.

Methods

We carried out a prospective observational cohort study including nulliparous pregnant women in a Norwegian university hospital. Participants underwent clinical examinations, including pelvic organ prolapse quantification system (POP-Q) and transperineal ultrasound at gestational week 21 and at 6 weeks postpartum. Background and obstetrical information was obtained from an electronic questionnaire and from the patient’s electronic medical file respectively. Associations were estimated using logistic regression analyses. The dependent variable was aPOP, defined as POP-Q stage ≥2 at 6 weeks postpartum. Independent variables were mid-pregnancy measurements of selected POP-Q variables and levator hiatus area (LHarea), delivery route, and the presence of major levator ani muscle (LAM) injuries at 6 weeks postpartum.

Results

A larger LHarea, a more distensible LAM, a longer distance from the meatus urethra to the anus (Gh + Pb) and a more caudal position of the anterior vaginal wall (Ba) at mid-pregnancy were risk factors for aPOP at 6 weeks postpartum, whereas delivery route and the presence of major LAM injuries were not.

Conclusion

Prelabor differences in the pelvic floor rather than obstetrical events were risk factors for aPOP at 6 weeks postpartum.

Keywords

Pelvic organ prolapse Pelvic floor POP Postpartum Pregnancy 

Notes

Acknowledgements

The authors would like to thank the women who participated in the study and midwife Tone Breines Simonsen, who administered the assembling and follow-up of the cohort. We would also like to thank the physiotherapists Gunvor Hilde and Kristin Gjestland for data analysis of the ultrasound volumes.

Compliance with ethical standards

Ethical approval

The Regional Ethics Committee (REK Southeast D 2009/170) and the Akershus University Hospital Privacy Ombudsman (2799026) approved the study. All participants gave their written informed consent before entering the study.

All authors have revised the drafted article critically for important intellectual content and have approved the submitted article.

Conflicts of interest

None.

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Copyright information

© The International Urogynecological Association 2018

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyAkershus University HospitalLørenskogNorway
  2. 2.Division of Gynecology and ObstetricsOslo University HospitalOsloNorway
  3. 3.Faculty of Health SciencesOslo and Akershus University College of Applied SciencesOsloNorway
  4. 4.Department of Sports MedicineNorwegian School of Sport SciencesOsloNorway
  5. 5.Faculty Division Akershus University HospitalUniversity of OsloOsloNorway

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