Abstract
An 81-year-old woman presented with symptoms of recurrent urinary tract infections, urge incontinence and nocturia. Cystoscopy performed revealed a whitish plaque lesion on the fundus and right lateral wall of the bladder. The histology of the biopsy confirmed the diagnosis of leukoplakia vesicae of the bladder. The plan is to follow her up with repeat cystoscopy and biopsy in 6 months. The literature search revealed very little information on the pathogenesis and prognosis of this condition due to its rare occurrence. Analysis of the literature signifies the association of chronic irritation due to recurrent urinary tract infections being the commonest cause of leukoplakia vesicae. The recommended long-term follow-up and surveillance based on the literature review is by cystoscopy with or without biopsy.
References
Roehrborn CG, Teigland CM, Spense HM (1988) Progression of leukoplakia of bladder to squamous cell carcinoma 19 years after complete urinary diversion. J Urol 140(3):603–604
Eyup G, Banu Y, Cengiz M (2002) Extensive bilateral renal pelvis, ureter and bladder leukoplakia—case report. Int J Urol 9(11):653–655
Staack A, Schlechte H, Sachs M, Kristiansen G, Burkhardt M, Schnorr D (2006) Clinical value of vesical leukoplakia and evaluation of the neoplastic risk by mutation analyses of the tumour suppressor gene TP53. Int J Urol 13(8):1092–1097
Neimark AL, Ii’inskaia EV, Lebedeva RN, Taranina TC (2009) Leukoplakia vesicae in females: diagnosis and treatment. Urologiia 2:18–22
Hojgaard AD, Jensen AL (1991) A case of vesical leukoplakia—case report. Acta Obstet Gynecol Scand 70:623–624
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kasianandan, A., Kannan, K. Leukoplakia of the bladder: a case report and literature review. Int Urogynecol J 23, 131–133 (2012). https://doi.org/10.1007/s00192-011-1491-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00192-011-1491-3