Abstract
Introduction and hypothesis
To compare depressive symptoms in women with and without prolapse and evaluate impact on quality of life.
Methods
This is a secondary analysis of a case–control study assessing the effect of prolapse on body image. Cases had prolapse and sought surgery (Pelvic Organ Prolapse Quantification stage ≥2). Controls had stage ≤1. Subjects completed the Pelvic Floor Impact Questionnaire (PFIQ), Pelvic Floor Distress Inventory, and the Patient Health Questionnaire-9 (PHQ-9) at baseline. Cases completed measures 6 months post-operatively. We report: (1) the comparison of cases and controls at baseline and (2) comparison of baseline and post-operative scores in cases.
Results
Baseline questionnaires were completed by 75 cases and 65 controls; 57 cases completed post-operative measures. Cases were 5-fold more likely than controls to have depressive symptoms. Cases with depressive symptoms had higher PFIQ scores than cases without symptoms. PHQ-9 scores improved post-operatively.
Conclusions
Depressive symptoms are common in women with prolapse and a decrease following surgical treatment.
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This research was funded in part by NIH/NICHD 2K12 HD43441-06 (Dr. Ghetti) and the 2007 American Urogynecologic Society Foundation–Astellas Research Award (Dr. Lowder).
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Ghetti, C., Lowder, J.L., Ellison, R. et al. Depressive symptoms in women seeking surgery for pelvic organ prolapse. Int Urogynecol J 21, 855–860 (2010). https://doi.org/10.1007/s00192-010-1106-4
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DOI: https://doi.org/10.1007/s00192-010-1106-4