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Microstructural development during additive manufacturing of biomedical grade Ti-6Al-4V alloy by three-dimensional binder jetting: material aspects and mechanical properties

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Abstract

Additive manufacturing (AM) of biomedical materials provides enormous opportunities to fabricate multifunctional and structurally designed frameworks for tissue engineering, such as dental implants and bone substitutes. Despite several advantages of the binder jet 3D printing technology over other AM methods, for example, no limitations in materials selection, high materials recycling efficiency, no thermal stress development, no need to support materials, and the possibility of fabrication of printing functionally graded materials, the fabrication of biomedical-grade titanium alloys with high-density, fine microstructure, and low pickup of impurities is still challenging. This work presents the effects of powder particle size and 3D printing conditions on the microstructural features and mechanical properties of Ti-6Al-4V alloy. The formation of large and inter-aggregate pores during binder jetting is demonstrated and discussed. Design and selection of particle size distribution with a mean diameter of ~20 μm and large span and positive skewness are proposed to minimize binder-induced powder aggregation and fabricate green parts with a density of 65±1% PFD (pore-free density). Dilatometric studies under a partial pressure of argon (0.1 bar) determine that sintering just above the α/β transus temperature (~980 °C) provides a high strain rate to remove pores, but high-temperature sintering (≥1250 °C) is required to attain 97% PFD. The successful fabrication of high-density Ti-6Al-4V parts (≥96% PFD) with the microstructure comparable to metal injection molding (MIM) titanium parts (≈100 μm α grains + β lattes) is demonstrated. The tensile strength and elongation values fall in the range of 880±50 MPa and 6±2% (depending on the processing condition), which is comparable with metal injection molded parts and superior to the laser powder bed fusion technology concerning ductility. The content of carbon (<0.02 wt.%) and nitrogen (0.01 wt.%) also falls in the standard region of metal injection molding. However, oxygen pickup during sintering moderately increases the oxygen content (for 30–50%) over the standard level. The concentration of interstitials entrapped in the metal is comparable to that of parts manufactured by the powder bed fusion process, but the mechanical properties are better matched with the commercial titanium alloy. The fabrication of the titanium alloy as per the ASTM F2885 standard provides an excellent opportunity for the binder jetting process to develop custom-made biomaterials.

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References

  1. Gibson I, Rosen D, Stucker B (2015) Additive manufacturing technologies: 3D printing, rapid prototyping, and direct digital manufacturing, second edition. Johnson Matthey Technol Rev 59:193–198. https://doi.org/10.1007/978-1-4939-2113-3

    Article  Google Scholar 

  2. Parab ND, Barnes JE, Zhao C et al (2019) Real time observation of binder jetting printing process using high-speed X-ray imaging. Sci Rep 9:2499. https://doi.org/10.1038/s41598-019-38862-7

    Article  Google Scholar 

  3. Zuo X, Zhang W, Chen Y et al (2022) Wire-based directed energy deposition of NiTiTa shape memory alloys: microstructure, phase transformation, electrochemistry, X-ray visibility and mechanical properties. Addit Manuf 59:103115. https://doi.org/10.1016/j.addma.2022.103115

    Article  Google Scholar 

  4. Li B, Wang L, Wang B et al (2022) Electron beam freeform fabrication of NiTi shape memory alloys: crystallography, martensitic transformation, and functional response. Mater Sci Eng A 843:143135. https://doi.org/10.1016/j.msea.2022.143135

    Article  Google Scholar 

  5. Mostafaei A, Elliott AM, Barnes JE et al (2021) Binder jet 3D printing—process parameters, materials, properties, modeling, and challenges. Prog Mater Sci 119:100707. https://doi.org/10.1016/j.pmatsci.2020.100707

    Article  Google Scholar 

  6. Moon J, Caballero AC, Hozer L et al (2001) Fabrication of functionally graded reaction infiltrated SiC-Si composite by three-dimensional printing (3DPTM) process. Mater Sci Eng A 298:110–119. https://doi.org/10.1016/s0921-5093(00)01282-x

    Article  Google Scholar 

  7. Barthel B, Hein SD, Aumund-Kopp C, Petzoldt F (2019) Influence of particle size distribution in metal binder jetting – Effects on the properties of green and sintered parts. In: Euro PM2019 Congress & Exhibition. Maastricht, Netherlands

  8. Rishmawi I, Salarian M, Vlasea M (2018) Tailoring green and sintered density of pure iron parts using binder jetting additive manufacturing. Addit Manuf 24:508–520. https://doi.org/10.1016/j.addma.2018.10.015

    Article  Google Scholar 

  9. Ziaee M, Tridas EM, Crane NB (2017) Binder-jet printing of fine stainless steel powder with varied final density. JOM 69:592–596. https://doi.org/10.1007/s11837-016-2177-6

    Article  Google Scholar 

  10. Verlee B, Dormal T, Lecomte-Beckers J (2012) Density and porosity control of sintered 316l stainless steel parts produced by additive manufacturing. Powder Metall 55:260–267. https://doi.org/10.1179/0032589912Z.00000000082

    Article  Google Scholar 

  11. Kumar A, Bai Y, Eklund A, Williams CB (2017) Effects of hot isostatic pressing on copper parts fabricated via binder jetting. Procedia Manufacturing, pp 935–944

    Google Scholar 

  12. Bai Y, Wagner G, Williams CB (2017) Effect of particle size distribution on powder packing and sintering in binder jetting additive manufacturing of metals. J Manuf Sci Eng Trans ASME 139:1–15. https://doi.org/10.1115/1.4036640

    Article  Google Scholar 

  13. Nandwana P, Elliott AM, Siddel D et al (2017) Powder bed binder jet 3D printing of Inconel 718: densification, microstructural evolution and challenges☆. Curr Opin Solid State Mater Sci 21:207–218. https://doi.org/10.1016/j.cossms.2016.12.002

    Article  Google Scholar 

  14. Mostafaei A, Behnamian Y, Krimer YL et al (2016) Effect of solutionizing and aging on the microstructure and mechanical properties of powder bed binder jet printed nickel-based superalloy 625. Mater Des 111:482–491. https://doi.org/10.1016/j.matdes.2016.08.083

    Article  Google Scholar 

  15. Sheydaeian E, Fishman Z, Vlasea M, Toyserkani E (2017) On the effect of throughout layer thickness variation on properties of additively manufactured cellular titanium structures. Addit Manuf 18:40–47. https://doi.org/10.1016/j.addma.2017.08.017

    Article  Google Scholar 

  16. Wiria FE, Shyan JYM, Lim PN et al (2010) Printing of titanium implant prototype. Mater Des 31:S101–S105. https://doi.org/10.1016/j.matdes.2009.12.050

    Article  Google Scholar 

  17. Dourandish M, Simchi A, Godlinski D (2008) Rapid manufacturing of Co-Cr-Mo implants by three- dimentional printing process for orthopedic applications. Iran J Pharm Sci 4:31–36

    Google Scholar 

  18. Dourandish M, Godlinski D, Simchi A (2007) 3D printing of biocompatible PM-materials. Mater Sci Forum 534–536:453–456. https://doi.org/10.4028/www.scientific.net/msf.534-536.453

    Article  Google Scholar 

  19. Mostafaei A, Rodriguez De Vecchis P, Buckenmeyer MJ et al (2019) Microstructural evolution and resulting properties of differently sintered and heat-treated binder-jet 3D-printed Stellite 6. Mater Sci Eng C 102:276–288. https://doi.org/10.1016/j.msec.2019.04.011

    Article  Google Scholar 

  20. Paranthaman MP, Shafer CS, Elliott AM et al (2016) Binder jetting: a novel NdFeB bonded magnet fabrication process. JOM 68:1978–1982. https://doi.org/10.1007/s11837-016-1883-4

    Article  Google Scholar 

  21. Caputo MP, Berkowitz AE, Armstrong A et al (2018) 4D printing of net shape parts made from Ni-Mn-Ga magnetic shape-memory alloys. Addit Manuf 21:579–588. https://doi.org/10.1016/j.addma.2018.03.028

    Article  Google Scholar 

  22. Cramer CL, Nandwana P, Yan J et al (2019) Binder jet additive manufacturing method to fabricate near net shape crack-free highly dense Fe-6.5 wt.% Si soft magnets. Heliyon 5:e02804. https://doi.org/10.1016/j.heliyon.2019.e02804

    Article  Google Scholar 

  23. Khorasani AM, Goldberg M, Doeven EH, Littlefair G (2015) Titanium in biomedical applications—properties and fabrication: a review. J Biomater Tissue Eng 5:593–619. https://doi.org/10.1166/jbt.2015.1361

    Article  Google Scholar 

  24. Salvador CAF, Maia EL, Costa FH et al (2022) A compilation of experimental data on the mechanical properties and microstructural features of Ti-alloys. Sci Data 9:188. https://doi.org/10.1038/s41597-022-01283-9

    Article  Google Scholar 

  25. Callegari B, Oliveira JP, Aristizabal K et al (2020) In-situ synchrotron radiation study of the aging response of Ti-6Al-4V alloy with different starting microstructures. Mater Charact 165:110400. https://doi.org/10.1016/j.matchar.2020.110400

    Article  Google Scholar 

  26. Olin C (2001) Titanium in cardiac and cardiovascular applications. In: Titanium in medicine: Material Science, Surface Science, Engineering, Biological Responses and Medical Applications. Springer-Verlag, Berlin Heidelberg GmbH, Berlin, pp 889–908

    Chapter  Google Scholar 

  27. Tamayo JA, Riascos M, Vargas CA, Baena LM (2021) Additive manufacturing of Ti6Al4V alloy via electron beam melting for the development of implants for the biomedical industry. Heliyon 7:e06892. https://doi.org/10.1016/j.heliyon.2021.e06892

    Article  Google Scholar 

  28. Zhang LC, Chen LY (2019) A review on biomedical titanium alloys: recent progress and prospect. Adv Eng Mater 21:1801215. https://doi.org/10.1002/adem.201801215

    Article  Google Scholar 

  29. Qian M, Xu W, Brandt M, Tang HP (2016) Additive manufacturing and postprocessing of Ti-6Al-4V for superior mechanical properties. MRS Bull 41:775–783. https://doi.org/10.1557/mrs.2016.215

    Article  Google Scholar 

  30. Nichols MR (2020) The pros & cons of powder bed fusion. Met Powder Rep 76:1–2. https://doi.org/10.1016/j.mprp.2020.04.004

    Article  Google Scholar 

  31. Osman İ, Gepek E (2021) Characterization of CP-titanium produced via binder jetting and conventional powder metallurgy. Rev Metal 57:e205. https://doi.org/10.3989/revmetalm.205

    Article  Google Scholar 

  32. Basalah A, Esmaeili S, Toyserkani E (2016) On the influence of sintering protocols and layer thickness on the physical and mechanical properties of additive manufactured titanium porous bio-structures. J Mater Process Technol 238:341–351. https://doi.org/10.1016/j.jmatprotec.2016.07.037

    Article  Google Scholar 

  33. Basalah A, Shanjani Y, Esmaeili S, Toyserkani E (2012) Characterizations of additive manufactured porous titanium implants. J Biomed Mater Res - Part B Appl Biomater 100(B):1970–1979. https://doi.org/10.1002/jbm.b.32764

    Article  Google Scholar 

  34. Wheat E, Vlasea M, Hinebaugh J, Metcalfe C (2018) Data related to the sinter structure analysis of titanium structures fabricated via binder jetting additive manufacturing. Data Br 20:1029–1038. https://doi.org/10.1016/j.dib.2018.08.135

    Article  Google Scholar 

  35. Polozov I, Sufiiarov V, Shamshurin A (2019) Synthesis of titanium orthorhombic alloy using binder jetting additive manufacturing. Mater Lett 243:88–91. https://doi.org/10.1016/j.matlet.2019.02.027

    Article  Google Scholar 

  36. Miyanaji H, Zhang S, Yang L (2018) A new physics-based model for equilibrium saturation determination in binder jetting additive manufacturing process. Int J Mach Tools Manuf 124:1–11. https://doi.org/10.1016/j.ijmachtools.2017.09.001

    Article  Google Scholar 

  37. Stevens E, Schloder S, Bono E et al (2018) Density variation in binder jetting 3D-printed and sintered Ti-6Al-4V. Addit Manuf 22:746–752. https://doi.org/10.1016/j.addma.2018.06.017

    Article  Google Scholar 

  38. Dilip JJS, Miyanaji H, Lassell A et al (2017) A novel method to fabricate TiAl intermetallic alloy 3D parts using additive manufacturing. Def Technol 13:72–76. https://doi.org/10.1016/j.dt.2016.08.001

    Article  Google Scholar 

  39. Yadav P, Bock T, Fu Z et al (2019) Novel hybrid printing of porous TiC/Ti6Al4V composites. Adv Eng Mater 21:1900336. https://doi.org/10.1002/adem.201900336

    Article  Google Scholar 

  40. Yadav P, Fu Z, Knorr M, Travitzky N (2020) Binder jetting 3D printing of titanium aluminides based materials: a feasibility study. Adv Eng Mater 22:2000408. https://doi.org/10.1002/adem.202000408

    Article  Google Scholar 

  41. Sheydaeian E, Toyserkani E (2018) Additive manufacturing functionally graded titanium structures with selective closed cell layout and controlled morphology. Int J Adv Manuf Technol 96:3459–3469. https://doi.org/10.1007/s00170-018-1815-2

    Article  Google Scholar 

  42. Merkus HG (2009) Particle size measurements: fundamentals, practice, quality. Springer Science+Business Media B.V

    Google Scholar 

  43. Chen H, Wei Q, Zhang Y et al (2019) Powder-spreading mechanisms in powder-bed-based additive manufacturing: experiments and computational modeling. Acta Mater 179:158–171. https://doi.org/10.1016/j.actamat.2019.08.030

    Article  Google Scholar 

  44. Nor NHM, Muhamad N, Ihsan AKAM, Jamaludin KR (2013) Sintering parameter optimization of Ti-6Al-4V metal injection molding for highest strength using palm stearin binder. In: Procedia Engineering. Elsevier B V, pp 359–364

    Google Scholar 

  45. Liu S, Shin YC (2019) Additive manufacturing of Ti6Al4V alloy: a review. Mater Des 164:107552. https://doi.org/10.1016/j.matdes.2018.107552

    Article  Google Scholar 

  46. Composition C, Properties P (2020) ATI 6-4: Ti-6Al-4V alloy. Alloy Dig 69:Ti-171. https://doi.org/10.31399/asm.ad.ti171

    Article  Google Scholar 

  47. Nakajima H, Koiwa M (1991) Diffusion in titanium. ISIJ Int 31:757–766. https://doi.org/10.2355/isijinternational.31.757

    Article  Google Scholar 

  48. German RM (1996) Sintering: theory and practice, 1st edn. Wiley-Interscience

    Google Scholar 

  49. Benzing J, Hrabe N, Quinn T et al (2019) Hot isostatic pressing (HIP) to achieve isotropic microstructure and retain as-built strength in an additive manufacturing titanium alloy (Ti-6Al-4V). Mater Lett 257:126690. https://doi.org/10.1016/j.matlet.2019.126690

    Article  Google Scholar 

  50. Bolzoni L, Ruiz-Navas EM, Zhang D, Gordo E (2012) Modification of sintered titanium alloys by hot isostatic pressing. Key Eng Mater 520:63–69. https://doi.org/10.4028/www.scientific.net/KEM.520.63

    Article  Google Scholar 

  51. German RM (2013) Progress in titanium metal powder injection molding. Materials (Basel) 6:3641–3662. https://doi.org/10.3390/ma6083641

    Article  Google Scholar 

  52. Murray JL, Wriedt HA (1987) The O-Ti (oxygen-titanium) system. J Phase Equilibria 8:148–165. https://doi.org/10.1007/BF02873201

    Article  Google Scholar 

  53. Bignolas JB, Bujor M, Bardolle J (1981) A study of the early stages of the kinetics of titanium oxidation by auger electron spectroscopy and mirror electron microscopy. Surf Sci 108:L453–L459. https://doi.org/10.1016/0039-6028(81)90442-8

    Article  Google Scholar 

  54. Nikiel P, Wróbel M, Szczepanik S et al (2021) Microstructure and mechanical properties of titanium grade 23 produced by selective laser melting. Arch Civ Mech Eng 21:152. https://doi.org/10.1007/s43452-021-00304-5

    Article  Google Scholar 

  55. Merkushev A, Ilyinikh M, State F et al (2017) Effect of oxygen and nitrogen contents on the structure of the ti-6al-4v alloy manufactured by selective laser melting. In: Proceedings III International Scientific Conference: Material Science. Nonequilibrium Phase Transformations, pp 101–103

    Google Scholar 

  56. Ogden HR, Jaffee RI (1955) The effects of carbon, oxygen and nitrogen on the mechanical properties of titanium and titanium alloys. Titan Metall Lab 20:101

    Google Scholar 

  57. Zhang XC, Zhong F, Shao JB et al (2016) Failure mechanism and mode of Ti-6Al-4V alloy under uniaxial tensile loading: experiments and micromechanical modeling. Mater Sci Eng A 676:536–545. https://doi.org/10.1016/j.msea.2016.09.019

    Article  Google Scholar 

  58. Moridi A, Demir AG, Caprio L et al (2019) Deformation and failure mechanisms of Ti–6Al–4V as built by selective laser melting. Mater Sci Eng A 768:138456. https://doi.org/10.1016/j.msea.2019.138456

    Article  Google Scholar 

  59. do Prado RF, Esteves GC, ELDS S et al (2018) In vitro and in vivo biological performance of porous Ti alloys prepared by powder metallurgy. PLoS One 13:e0196169. https://doi.org/10.1371/journal.pone.0196169

    Article  Google Scholar 

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Funding

AS acknowledges the Alexander von Humboldt Foundation for granting a research fellowship to carry out this study at the Fraunhofer IFAM institute. He also thanks Sharif University of Technology for providing facilities to perform complementary analyses (QA970816). The authors certify that they have no affiliations with or involvement in any organization or entity with any financial or non-financial interest in the subject matter or materials discussed in this manuscript.

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Authors and Affiliations

  1. Department of Materials Science and Engineering, Sharif University of Technology, Azadi Avenue, Tehran, 14588 89694, Iran

    Abdolreza Simchi

  2. Fraunhofer Institute for Manufacturing Engineering and Applied Materials Research (IFAM), Wiener Str. 12, 28359, Bremen, Germany

    Abdolreza Simchi, Frank Petzoldt, Thomas Hartwig, Sebastian Boris Hein, Bastian Barthel & Lea Reineke

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  1. Abdolreza Simchi
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  2. Frank Petzoldt
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Contributions

Abdolreza Simchi: conceptualization, methodology, investigation, formal analysis, data curing, validation, writing—original draft, and writing—review and editing. Frank Petzoldt: conceptualization, resources, project administration, and financial acquisition. Thomas Hartwig: formal analysis and data curation. Sebastian Boris Hein: visualization, data curation, and writing—review and editing. Bastian Barthel: visualization and software.

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Simchi, A., Petzoldt, F., Hartwig, T. et al. Microstructural development during additive manufacturing of biomedical grade Ti-6Al-4V alloy by three-dimensional binder jetting: material aspects and mechanical properties. Int J Adv Manuf Technol 127, 1541–1558 (2023). https://doi.org/10.1007/s00170-023-11661-1

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