Lithography-based additive manufacture of ceramic biodevices with design-controlled surface topographies

  • Adrián de Blas Romero
  • Markus Pfaffinger
  • Gerald Mitteramskogler
  • Martin Schwentenwein
  • Christopher Jellinek
  • Johannes Homa
  • Andrés Díaz LantadaEmail author
  • Jürgen Stampfl
Open Access


The possibility of manufacturing textured materials and devices, with surface properties controlled from the design stage, instead of being the result of machining processes or chemical attacks, is a key factor for the incorporation of advanced functionalities to a wide set of micro- and nano-systems. High-precision additive manufacturing (AM) technologies based on photopolymerization, together with the use of fractal models linked to computer-aided design tools, allow for a precise definition of final surface properties. However, the polymeric master parts obtained with most commercial systems are usually inadequate for biomedical purposes and their limited strength and size prevents many potential applications. On the other hand, additive manufacturing technologies aimed at the production of final parts, normally based on layer-by-layer melting or sintering ceramic or metallic powders, do not always provide the required precision for obtaining controlled micro-structured surfaces with high-aspect-ratio details. Towards the desired degree of precision and performance, lithography-based ceramic manufacture is a remarkable option, as we discuss in the present study, which presents the development of two different micro-textured biodevices for cell culture. Results show a remarkable control of the surface topography of ceramic parts and the possibility of obtaining design-controlled micro-structured surfaces with high-aspect-ratio micro-metric details.


Fractals Surface topography Material texture Materials design Computer-aided design Additive manufacturing Lithography-based ceramic manufacture 


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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Adrián de Blas Romero
    • 1
  • Markus Pfaffinger
    • 2
  • Gerald Mitteramskogler
    • 3
  • Martin Schwentenwein
    • 3
  • Christopher Jellinek
    • 3
  • Johannes Homa
    • 3
  • Andrés Díaz Lantada
    • 1
    Email author
  • Jürgen Stampfl
    • 2
    • 4
  1. 1.UPM Product Development Lab, Mechanical Engineering DepartmentUniversidad Politécnica de Madrid (TU Madrid,
  2. 2.Christian Doppler Laboratory for Digital and Restorative DentistryViennaAustria
  3. 3.Lithoz GmbHViennaAustria
  4. 4.Institute of Materials Science and TechnologyTU WienWienAustria

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