Abstract
Purpose
The purpose of this study was to assess the clinical and patient-reported outcomes of a customised, individually made (CIM) bi-compartmental knee arthroplasty (BKA).
Methods
A prospectively recruited cohort of 79 patients was implanted with a CIM-BKA (patello-femoral plus either medial or lateral tibio-femoral, iDuo G2 system, Conformis, Billerica MA) at eight centres in the US and Germany. Patients were assessed for the 2011 KSS, KOOS, and ROM pre-operatively and at 2 weeks, 6 weeks, 12 weeks, 1 year, and 2 years post-operatively.
Results
The objective KSS score significantly improved from 69 at the pre-operative visit, to 94 at the 2-year post-operative time-point. Similar improvements were observed for the KSS function and satisfaction domains. Significant improvements from pre-operative levels were observed across all five domains of the KOOS. Two patients have undergone surgery to revise their CIM-BKA implant to total knees, resulting in a survivorship rate of 97.5% at an average follow-up of 2.6 years.
Conclusions
CIM-BKA compares favourably to published scores as well as revision rates for previously available monolithic OTS-BKA implants. CIM-BKA implants provide surgeons with a viable and patient-specific monolithic implant solution as an option for patients presenting with bi-compartmental disease, who might, otherwise, be treated by performing uni-condylar + patello-femoral joint or bicruciate sparing TKA surgeries. Longer follow-up and higher numbers have to be awaited for further validation of these encouraging early results.
Level of evidence
3b (individual case-controlled study).
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References
Beckmann J, Steinert A, Zilkens C, Zeh A, Schnurr C, Schmitt-Sody M et al (2016) Partial replacement of the knee joint with patient-specific instruments and implants (ConforMIS iUni, iDuo). Orthopade 45:322–330
Benazzo F, Rossi SM, Ghiara M (2014) Partial knee arthroplasty: patellofemoral arthroplasty and combined unicompartmental and patellofemoral arthroplasty implants–general considerations and indications, technique and clinical experience. Knee 21(Suppl 1):S43–46
Bourne RB, Chesworth BM, Davis AM, Mahomed NN, Charron KD (2010) Patient satisfaction after total knee arthroplasty: who is satisfied and who is not? Clin Orthop Relat Res 468:57–63
Carpenter DP, Holmberg RR, Quartulli MJ, Barnes CL (2014) Tibial plateau coverage in UKA: a comparison of patient specific and off-the-shelf implants. J Arthroplasty 15:15. https://doi.org/10.1016/j.arth.2014.03.026
Christensen JC, Brothers J, Stoddard GJ, Anderson MB, Pelt CE, Gililland JM et al (2017) Higher frequency of reoperation with a new bicruciate-retaining total knee arthroplasty. Clin Orthop Relat Res 475:62–69
Demange MK, Von Keudell A, Probst C, Yoshioka H, Gomoll AH (2015) Patient-specific implants for lateral unicompartmental knee arthroplasty. Int Orthop 39:1519–1526
Engh GA, Parks NL, Whitney CE (2014) A prospective randomized study of bicompartmental vs. total knee arthroplasty with functional testing and short term outcome. J Arthroplasty. https://doi.org/10.1016/j.arth.2014.04.016
Fitz W (2009) Unicompartmental knee arthroplasty with use of novel patient-specific resurfacing implants and personalized jigs. J Bone Jt Surg Am 91(Suppl 1):69–76
Heekin RD, Fokin AA (2014) Incidence of bicompartmental osteoarthritis in patients undergoing total and unicompartmental knee arthroplasty: is the time ripe for a less radical treatment? J Knee Surg 27:77–81
Johnson TC, Tatman PJ, Mehle S, Gioe TJ (2012) Revision surgery for patellofemoral problems: should we always resurface? Clin Orthop Relat Res 470:211–219
Kamath AF, Levack A, John T, Thomas BS, Lonner JH (2014) Minimum two-year outcomes of modular bicompartmental knee arthroplasty. J Arthroplasty 29:75–79
Morrison TA, Nyce JD, Macaulay WB, Geller JA (2011) Early adverse results with bicompartmental knee arthroplasty: a prospective cohort comparison to total knee arthroplasty. J Arthroplasty 26:35–39
Muller M, Matziolis G, Falk R, Hommel H (2012) The bicompartmental knee joint prosthesis Journey Deuce: failure analysis and optimization strategies. Orthopade 41:894–904
Noble PC, Conditt MA, Cook KF, Mathis KB (2006) The John Insall Award: patient expectations affect satisfaction with total knee arthroplasty. Clin Orthop Relat Res 452:35–43
Ogura T, Le K, Merkely G, Bryant T, Minas T (2019) A high level of satisfaction after bicompartmental individualized knee arthroplasty with patient-specific implants and instruments. Knee Surg Sports Traumatol Arthrosc 27:1487–1496
Palumbo BT, Henderson ER, Edwards PK, Burris RB, Gutierrez S, Raterman SJ (2011) Initial experience of the Journey-Deuce bicompartmental knee prosthesis: a review of 36 cases. J Arthroplasty 26:40–45
Parratte S, Pauly V, Aubaniac JM, Argenson JN (2010) Survival of bicompartmental knee arthroplasty at 5–23 years. Clin Orthop Relat Res 468:64–72
Shah SM, Dutton AQ, Liang S, Dasde S (2013) Bicompartmental versus total knee arthroplasty for medio-patellofemoral osteoarthritis: a comparison of early clinical and functional outcomes. J Knee Surg 26:411–416
Steinert AF, Beckmann J, Holzapfel BM, Rudert M, Arnholdt J (2017) Bicompartmental individualized knee replacement: use of patient-specific implants and instruments (iDuo). Oper Orthop Traumatol 29:51–58
Tan SM, Dutton AQ, Bea KC, Kumar VP (2013) Bicompartmental versus total knee arthroplasty for medial and patellofemoral osteoarthritis. J Orthop Surg (Hong Kong) 21:281–284
Thienpont E, Price A (2013) Bicompartmental knee arthroplasty of the patellofemoral and medial compartments. Knee Surg Sports Traumatol Arthrosc 21:2523–2531
Tria AJ Jr (2013) Bicompartmental knee arthroplasty: the clinical outcomes. Orthop Clin North Am 44(281–286):vii
Wang H, Foster J, Franksen N, Estes J, Rolston L (2018) Gait analysis of patients with an off-the-shelf total knee replacement versus customised bi-compartmental knee replacement. Int Orthop 42:805–810
Yamabe E, Ueno T, Miyagi R, Watanabe A, Guenzi C, Yoshioka H (2013) Study of surgical indication for knee arthroplasty by cartilage analysis in three compartments using data from Osteoarthritis Initiative (OAI). BMC Musculoskelet Disord 14:194
Funding
This study was externally funded by Conformis.
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All authors of the multicenter study received honoraria for patient enrollment and honoraria as consultants of Conformis which might influence this work.
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IRB/Ethics Committee approval was obtained from all participating sites.
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All patients signed an informed consent prior to participating in the study.
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Beckmann, J., Steinert, A.F., Huber, B. et al. Customised bi-compartmental knee arthroplasty shows encouraging 3-year results: findings of a prospective, multicenter study. Knee Surg Sports Traumatol Arthrosc 28, 1742–1749 (2020). https://doi.org/10.1007/s00167-019-05595-z
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DOI: https://doi.org/10.1007/s00167-019-05595-z