Abstract
Purpose
The purpose of this retrospective study was to investigate the rate of non-union after medial open-wedge high tibial osteotomy (HTO) with the Tomofix® plate. In addition, risk factors with a possible influence on the development of a non-union were analysed.
Methods
Between 2006 and 2008, a total of 186 medial open-wedge HTOs were performed in 182 patients.
Results
Ten cases of non-union (5.4%) were recorded. Risk factors with a statistically significant influence on the development of a non-union included smoking, body mass index and fracture of the lateral cortical hinge. No influence was detected for the factors age, degree of correction, concomitant diseases, postoperative complications, drug use, additionally performed procedures and use of a temporary lag screw.
Conclusion
Within this study, it could be demonstrated that the rate of non-union in medial open-wedge HTO is not higher than in the lateral closed-wedge technique. Concerning the detected risk factors, the importance of the preservation of the lateral cortex is emphasised. In addition, it is necessary to discuss the risk of non-union with smokers and overweight patients when planning the therapy. Finally, it should be considered to perform iliac crest bone grafting in these high-risk patients a priori.
Level of evidence
IV.
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References
Amendola A, Bonasia DE (2010) Results of high tibial osteotomy: review of the literature. Int Orthop 34:155–160
Aydogdu S, Cullu E, Arac N et al (2000) Prolonged peroneal nerve dysfunction after high tibial osteotomy: pre- and postoperative electrophysiological study. Knee Surg Sports Traumatol Arthrosc 8:305–308
Brown CW, Orme TJ, Richardson HD (1986) The rate of pseudarthrosis (surgical nonunion) in patients who are smokers and patients who are nonsmokers: a comparison study. Spine (Phila Pa 1976) 11:942–943
Cameron HU, Welsh RP, Jung YB, Noftall F (1993) Repair of nonunion of tibial osteotomy. Clin Orthop Relat Res 278:167–169
Cobb TK, Gabrielsen TA, Campbell DC 2nd et al (1994) Cigarette smoking and nonunion after ankle arthrodesis. Foot Ankle Int 15:64–67
Coventry MB (1984) Upper tibial osteotomy. Clin Orthop Relat Res 182:46–52
Coventry MB, Ilstrup DM, Wallrichs SL (1993) Proximal tibial osteotomy. A critical long-term study of eighty-seven cases. J Bone Joint Surg Am 75:196–201
Gaasbeek RD, Welsing RT, Verdonschot N et al (2005) Accuracy and initial stability of open- and closed-wedge high tibial osteotomy: a cadaveric RSA study. Knee Surg Sports Traumatol Arthrosc 13:689–694
Galla M, Lobenhoffer P, Staubli AE (2006) Die valgisierende öffnende Umstellungsosteotomie der proximalen Tibia mit Plattenfixateur. In: Lobenhoffer P, Agneskirchner JD, Galla M (eds) Kniegelenknahe Osteotomien. Indikation, Planung, Operationstechnik mit Plattenfixateuren. Thieme, Stuttgart, pp 51–64
Green E, Lubahn JD, Evans J (2005) Risk factors, treatment, and outcomes associated with nonunion of the midshaft humerus fracture. J Surg Orthop Adv 14:64–72
Hernigou P, Ma W (2001) Open wedge tibial osteotomy with acrylic bone cement as bone substitute. Knee 8:103–110
Hoogendoorn JM, Simmermacher RK, Schellekens PP, van der Werken C (2002) Rauchen ist nachteilig für die Heilung von Knochen und Weichteilen. Unfallchirurg 105:76–81
Hunt N, Watts M, Hayes D et al (2005) Closing wedge high tibial osteotomy: review of 374 cases. J Bone Joint Surg Br 87-B:346
King AR, Moran SL, Steinmann SP (2007) Humeral nonunion. Hand Clin 23:449–456
Lee C, Dorcil J, Radomisli TE (2004) Nonunion of the spine: a review. Clin Orthop Relat Res 419:71–75
Lobenhoffer P, Agneskirchner JD (2003) Improvements in surgical technique of valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 11:132–138
Lobenhoffer P, Agneskirchner J, Zoch W (2004) Die öffnende valgisierende Osteotomie der proximalen Tibia mit Fixation durch einen medialen Plattenfixateur. Orthopade 33:153–160
Lobenhoffer P (2009) Die öffnende Tibiakopfosteotomie zur Behandlung der monokompartimentalen Gonarthrose. Arthroskopie 22:223–231
Miller BS, Dorsey WO, Bryant CR, Austin JC (2005) The effect of lateral cortex disruption and repair on the stability of the medial opening wedge high tibial osteotomy. Am J Sports Med 33:1552–1557
Miller BS, Downie B, McDonough EB, Wojtys EM (2009) Complications after medial opening wedge high tibial osteotomy. Arthroscopy 25:639–646
Naudie D, Bourne RB, Rorabeck CH, Bourne TJ (1999) The Install Award. Survivorship of the high tibial valgus osteotomy. A 10- to -22-year followup study. Clin Orthop Relat Res 367:18–27
Noyes FR, Mayfield W, Barber-Westin SD et al (2006) Opening wedge high tibial osteotomy: an operative technique and rehabilitation program to decrease complications and promote early union and function. Am J Sports Med 34:1262–1273
Pape D, Adam F, Rupp S et al (2004) Stabilität, Knochenheilung und Korrekturverlust nach valgisierender Tibiakopfumstellung. Eine Röntgenstereometrieanalyse. Orthopäde 33:208–217
Reischl N, Wahl P, Jacobi M et al (2009) Infections after high tibial open wedge osteotomy: a case control study. Arch Orthop Trauma Surg 129:1483–1487
Rodriguez-Merchan EC, Forriol F (2004) Nonunion: general principles and experimental data. Clin Orthop Relat Res 419:4–12
Runkel M, Rommens PM (2000) Pseudarthrosen. Unfallchirurg 103:51–63
Seide K, Wenzl ME, Wolter D, Jürgens C (2001) Posttraumatische Pseudarthrosen und Fehlstellungen des distalen Unterschenkels. Trauma und Berufskrankheit 4:301–304
Spahn G (2004) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653
Sprenger TR, Doerzbacher JF (2003) Tibial osteotomy for the treatment of varus gonarthrosis. Survival and failure analysis to 22 years. J Bone Joint Surg Am 85-A:469–474
Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia–early results in 92 cases. Injury 34(Suppl 2):B55–B62
Takeuchi R, Ishikawa H, Aratake M et al (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53
Tjornstrand B, Hagstedt B, Persson BM (1978) Results of surgical treatment for non-union after high tibial osteotomy in osteoarthritis of the knee. J Bone Joint Surg Am 60:973–977
Tunggal JA, Higgins GA, Waddell JP (2010) Complications of closing wedge high tibial osteotomy. Int Orthop 34:255–261
Valkering KP, van den Bekerom MP, Kappelhoff FM, Albers GH (2009) Complications after tomofix medial opening wedge high tibial osteotomy. J Knee Surg 22:218–225
van den Bekerom MP, Patt TW, Kleinhout MY et al (2008) Early complications after high tibial osteotomy: a comparison of two techniques. J Knee Surg 21:68–74
Warden SJ, Morris HG, Crossley KM et al (2005) Delayed- and non-union following opening wedge high tibial osteotomy: surgeons’ results from 182 completed cases. Knee Surg Sports Traumatol Arthrosc 13:34–37
World Health Organisation (2000) WHO consultation on obesity. Obesity: preventing and managing the global epidemic. Geneva, Switzerland: WHO Technical Report Series 894
Yacobucci GN, Cocking MR (2008) Union of medial opening-wedge high tibial osteotomy using a corticocancellous proximal tibial wedge allograft. Am J Sports Med 36:713–719
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Meidinger, G., Imhoff, A.B., Paul, J. et al. May smokers and overweight patients be treated with a medial open-wedge HTO? Risk factors for non-union. Knee Surg Sports Traumatol Arthrosc 19, 333–339 (2011). https://doi.org/10.1007/s00167-010-1335-6
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DOI: https://doi.org/10.1007/s00167-010-1335-6