Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement

Abstract

Despite significant advances in intraoperative antimicrobial procedures, deep infection remains the most devastating complication following total joint arthroplasty. Clinical studies’ results and safety profile of antibiotic-loaded bone cement are discussed in this review. Antibiotic bone cement prophylaxis is a safe and effective strategy in reducing the risk of deep infection following primary total joint arthroplasty.

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Correspondence to Pietro Randelli.

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Randelli, P., Evola, F.R., Cabitza, P. et al. Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement. Knee Surg Sports Traumatol Arthrosc 18, 181–186 (2010). https://doi.org/10.1007/s00167-009-0921-y

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Keywords

  • Infection
  • Total knee arthroplasty
  • Antibiotic-loaded cement