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Outcome of renal allografts from non-heart-beating donors with delayed graft function

  • Brief Report
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Transplant International

Abstract.

Delayed graft function (DGF) in renal transplantation using non-heart-beating donors (NHBDs) usually exceeds 80%. There is debate whether DGF in this subgroup is associated with poor long-term outcome. Between 1 January1988 and 31 January 2000, 130 of 158 (82.3%) NHBD graft recipients with functioning grafts transplanted within our regional NHBD programme developed DGF. Overall graft survival and graft survival censored for recipient death was 113/130 (86.9%) versus 113/121 (93.4%) at year 1, 55/84 (65.5%) versus 55/64 (85.9%) at year 5 and 18/40 (45.0%) versus 18/28 (64.3%) at year 10 after transplantation. Seventeen grafts (13.1%) were lost due to rejection or graft nephropathy. Nine of these kidneys failed during the 1st year. Twenty-seven patients (20.8%) died with functioning grafts, eight within the 1st year after transplantation. In those patients who survived, DGF was associated with excellent long-term outcome in this study. The number of grafts lost due to recipient death exceeded those lost due to rejection or graft nephropathy.

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Authors and Affiliations

  1. 39 Arragon Gardens, Streatham, London, SW16 5LY, UK, , , , ,

    Clemens Gerstenkorn

  2. Renal and Transplant Unit, Guy's Hospital, London, UK, , , , ,

    David Deardon & Geoffrey C. Koffman

  3. Renal and Transplant Unit, St. Mary's Hospital, London, UK, , , , ,

    Vassilios E. Papalois

  4. Renal and Transplant Unit, St. Helier Hospital, Carshalton, Surrey, UK, , , , ,

    Peter A. Andrews

Authors
  1. Clemens Gerstenkorn
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  2. David Deardon
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  3. Geoffrey C. Koffman
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  4. Vassilios E. Papalois
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  5. Peter A. Andrews
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Gerstenkorn, C., Deardon, D., Koffman, G.C. et al. Outcome of renal allografts from non-heart-beating donors with delayed graft function. Transpl Int 15, 660–663 (2002). https://doi.org/10.1007/s00147-002-0471-4

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  • DOI: https://doi.org/10.1007/s00147-002-0471-4

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