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Allogene Meniskustransplantation

Allogenic meniscus transplantation

  • Leitthema
  • Published:
Arthroskopie Aims and scope

Zusammenfassung

Basierend auf dem aktuellen Kenntnisstand und den klinischen Erfahrungen scheint die Transplantation von allogenem Meniskusgewebe beim jungen symptomatischen postmeniskektomierten Patienten gerechtfertigt. Hierbei können kurzfristig eine deutliche Funktionsbesserung und Schmerzreduktion erreicht werden. Jedoch muss der Patient darüber aufgeklärt werden, dass langfristig eine Verschlechterung der Gelenkfunktion zu erwarten ist und das Belastungsverhalten entsprechend angepasst werden muss. Eine Vermeidung degenerativer Gelenkveränderungen durch die Meniskustransplantation lässt sich aktuell nicht belegen. Verbesserungen bei der Wahl der geeigneten Transplantatgröße und der operativen Verfahren und Verankerung haben das Potenzial, deutliche Verbesserungen im langfristigen klinischen Verlauf erreichen zu können.

Abstract

Based on current knowledge the transplantation of human donor meniscal tissue is warranted in young symptomatic postmeniscectomy patients. Significant improvement in knee function and pain reduction can be achieved in the short-term. However, patients must be counselled that deterioration in joint function must be expected with time. The onset of degenerative changes cannot be prevented with meniscus transplantation. Improvements in the selection of suitable meniscus size and surgical technique and fixation might offer the potential of substantial advances in long-term function following allogenic meniscus transplantation.

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Scheffler, S. Allogene Meniskustransplantation. Arthroskopie 24, 36–41 (2011). https://doi.org/10.1007/s00142-010-0597-9

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