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Severe panarteritis associated with drug abuse

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Abstract

A case of panarteritis with purpura fulminans, mononeuritis multiplex, gastrointestinal manifestation and presumably cardiac involvement in a previously healthy 22-year-old man with a history of drug abuse including cocaine, cannabinoids and methamphetamines is described. Histopathological examination of the gut led to the diagnosis of panarteritis without immune deposits. Antineutrophil antibodies were negative. Besides the drugs, no other possible cause of vasculitis was found. The patient recovered completely after 1 year. Drug abuse is a thus possible cause of severe extracerebral disabling vasculitis.

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Authors and Affiliations

  1. Division of Nephrology/ Intensive Care Medicine, Charité/Campus Virchow-Klinikum, Augustenburger Platz 1, D-13 353 Berlin, Germany email: martin.moecke@charite.de Tel. + 49 (30) 45053232 Fax + 49(30)45 05 39 13, , , , , , DE

    M. Möckel, D. Kampf & U. Frei

  2. Department of Pathology, Ernst von Bergmann Klinikum, Potsdam, Germany, , , , , , DE

    H. Lobeck

Authors
  1. M. Möckel
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  2. D. Kampf
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  3. H. Lobeck
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  4. U. Frei
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Additional information

Received: 23 February 1998 Final revision received: 27 July 1998 Accepted: 27 August 1998

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Möckel, M., Kampf, D., Lobeck, H. et al. Severe panarteritis associated with drug abuse. Intensive Care Med 25, 113–117 (1999). https://doi.org/10.1007/s001340050797

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  • DOI: https://doi.org/10.1007/s001340050797

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