Intensive Care Medicine

, 24:740 | Cite as

Survival in a case of life-threatening flecainide overdose

  • N. A. Hanley
  • J. P. Bourke
  • A. D. Gascoigne
Brief Report


Flecainide acetate is a potent class Ic anti-arrhythmic drug with major sodium channel blocking actions. On the surface electrocardiogram this results in QTc interval prolongation. Overdose with class Ic drugs (<0.1 % of total intoxications) is uncommon, but management is difficult and the mortality high [1]. Serious flecainide overdose is characterised by ventricular tachyarrhythmias, severe bradycardia and variable degrees of atrioventricular block. This report describes a case of life-threatening flecainide overdose in a previously fit individual, resulting in a combination of cardiac disturbances. The treatment options and management are discussed.

Key words

Flecainide Overdose Arrhythmias 


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Copyright information

© Springer-Verlag 1998

Authors and Affiliations

  • N. A. Hanley
    • 1
  • J. P. Bourke
    • 2
  • A. D. Gascoigne
    • 1
  1. 1.Royal Victoria InfirmaryIntensive Therapy UnitNewcastle-upon-TyneUK
  2. 2.Department of Academic CardiologyFreeman HospitalUK

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