Abstract
Ethylenediaminetetraacetic acid-dependent pseudothrombocytopenia (EDTA-PTCP) is the phenomenon of a spurious low platelet count due to antiplatelet antibodies that cause platelet clumping in blood anticoagulated with EDTA. We describe a case of EDTA-PTCP that appeared transiently with the development of sepsis. A 50-year-old man underwent Bentall's aortic root replacement for acute aortic dissection with aortic insufficiency. Postoperatively the patient suffered paralytic ileus followed by methicillin-resistant Staphylococcus aureus enteritis and septicemia with endotoxemia. EDTA-PTCP appeared with the development of sepsis, and disappeared with its resolution. To avoid incorrect diagnoses and inappropriate treatment, EDTA-PTCP should always be considered as a possible cause of reported low platelet counts, even in patients with sepsis.
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Received: 16 May 1999/Final revision received: 27 October 1999/Accepted: 2 November 1999
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Mori, M., Kudo, H., Yoshitake, S. et al. Transient EDTA-dependent pseudothrombocytopenia in a patient with sepsis. Intensive Care Med 26, 218–220 (2000). https://doi.org/10.1007/s001340050050
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DOI: https://doi.org/10.1007/s001340050050