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Epker JL, Valkenburg A, Kompanje EJO (2020) Double data and dubious conclusions, “Houston do we have a problem?”. Intensive Care Med. https://doi.org/10.1007/s00134-020-06315-9
Laserna A, Durán-Crane A, López-Olivo MA et al (2020) Pain management during the withholding and withdrawal of life support in critically ill patients at the end-of-life: a systematic review and meta-analysis. Intensive Care Med 46:1671–1682. https://doi.org/10.1007/s00134-020-06139-7
Mallett S, Clarke M (2002) The typical cochrane review: how many trials? How many participants? Int J Technol Assess Health Care 18:820–823. https://doi.org/10.1017/S0266462302000624
Mularski RA, Puntillo K, Varkey B et al (2009) Pain management within the palliative and end-of-life care experience in the ICU. Chest 135:1360–1369. https://doi.org/10.1378/chest.08-2328
del Rosario MA, Martín AS, Ortega JJ, Feria M (2001) Temporary sedation with midazolam for control of severe incident pain. J Pain Symptom Manage 21:439–442. https://doi.org/10.1016/s0885-3924(01)00254-8
Durán-Crane A, Laserna A, López-Olivo MA et al (2019) Clinical practice guidelines and consensus statements about pain management in critically ill end-of-life patients. Crit Care Med 47:1619–1626. https://doi.org/10.1097/CCM.0000000000003975
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Laserna, A., Cuenca, J.A., Fowler, C. et al. Pain management during the withholding and withdrawal of life support in critically ill patients at the end of life: a response to a comment. Intensive Care Med 47, 491–492 (2021). https://doi.org/10.1007/s00134-020-06344-4