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Severity of endothelial dysfunction is associated with the occurrence of hemorrhagic complications in COPD patients treated by extracorporeal CO2 removal

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References

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Acknowledgements

We thank Florence Desvard, Sebastien Bertil, Yann Burnel, Laurent Garcia and Aurore Habrias for their excellent technical assistance. We thank Clotilde Bailleul and Caroline Hauw-Berlemont for English language reviewing.

Funding

The study benefited from a grant from the Creative Research Fund (Air-Liquide Santé International).

Author information

Authors and Affiliations

  1. Service de Médecine Intensive - Réanimation, Hôpital Européen Georges Pompidou, Assistance Publique – Hôpitaux de Paris, 20 rue Leblanc, 75015, Paris, France

    Jean-Luc Diehl & Jean Loup Augy

  2. Innovative Therapies in Haemostasis, INSERM UMR-S1140, Paris University, 75006, Paris, France

    Jean-Luc Diehl, Nadia Rivet, Coralie Guerin & David M. Smadja

  3. Hematology Department and Biosurgical Research Lab, Georges Pompidou European Hospital, 20 rue Leblanc, 75015, Paris, France

    Nadia Rivet & David M. Smadja

  4. Flow Cytometry Department, Curie Institute, 75006, Paris, France

    Coralie Guerin

  5. Emergency Department, Georges Pompidou European Hospital, 20 rue Leblanc, 75015, Paris, France

    Richard Chocron

  6. Paris Centre de Recherche Cardiovasculaire, INSERM UMR-S 970, Paris University, 75015, Paris, France

    Richard Chocron

Authors
  1. Jean-Luc Diehl
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  2. Jean Loup Augy
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  3. Nadia Rivet
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  4. Coralie Guerin
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  5. Richard Chocron
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  6. David M. Smadja
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Corresponding author

Correspondence to Jean-Luc Diehl.

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Conflicts of interest

Dr. Diehl reports grants and non-financial research support from ALung, non-financial research support from General Electric Healthcare and personal fees and non-financial research support from Xenios/Novalung (Fresenius Medical Care), all outside the submitted work. Other reported no conflicts of interests.

Ethics approval

Treatment with ECCO2R was performed as part of a specific registry (Registry on the EXperience of Extracorporeal CO2 Removal in Intensive Care Units, NCT02965079), benefiting from an approval (07 March 2016) from the Ethics Committee of the French Intensive Care Society.

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Diehl, JL., Augy, J.L., Rivet, N. et al. Severity of endothelial dysfunction is associated with the occurrence of hemorrhagic complications in COPD patients treated by extracorporeal CO2 removal. Intensive Care Med 46, 1950–1952 (2020). https://doi.org/10.1007/s00134-020-06138-8

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  • DOI: https://doi.org/10.1007/s00134-020-06138-8

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