Skip to main content
SpringerLink
Log in

Amphotericin B-deoxycholate as first-line antifungal therapy in critically ill patients: a word of caution

  • Correspondence
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

  • 1 Altmetric

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Roux D, Gaudry S, Dreyfuss D (2019) Conventional amphotericin B should remain in the armamentarium as a cheap and efficient waiting solution. Intensive Care Med 1:1–2. https://doi.org/10.1007/s00134-019-05782-z

    Article  Google Scholar 

  2. Lockhart SR (2019) Candida auris and multidrug resistance: defining the new normal. Fungal Genet Biol 131:103243. https://doi.org/10.1016/j.fgb.2019.103243

    Article  CAS  PubMed  Google Scholar 

  3. Eyre DW, Sheppard AE, Madder H et al (2018) A Candida auris outbreak and its control in an intensive care setting. N Engl J Med 379(14):1322–1331

    Article  Google Scholar 

  4. Lockhart SR, Etienne KA, Vallabhaneni S et al (2017) Simultaneous emergence of multidrug-resistant candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses. Clin Infect Dis 64(2):134–140

    Article  CAS  Google Scholar 

  5. Kuhn DM, George T, Chandra J et al (2002) Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins. Antimicrob Agents Chemother 46(6):1773–1780

    Article  CAS  Google Scholar 

  6. Oesterreicher Z, Eberl S, Zeitlinger M (2019) Impact of different antimycotics on cytokine levels in an in vitro aspergillosis model in human whole blood. Infection. https://doi.org/10.1007/s15010-019-01346-x

    Article  PubMed  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

  1. Department of Hematology and HSCT, National Institute of Hematology and Infectology, South-Pest Central Hospital, 5-7 Albert F u, Budapest, 1097, Hungary

    János Sinkó

Authors
  1. János Sinkó
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to János Sinkó.

Ethics declarations

Conflicts of interest

JS. Former and present advisor to Merck, Pfizer, Astellas and Gilead.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sinkó, J. Amphotericin B-deoxycholate as first-line antifungal therapy in critically ill patients: a word of caution. Intensive Care Med 46, 562–563 (2020). https://doi.org/10.1007/s00134-019-05880-y

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-019-05880-y

Search

Navigation