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Modulators of systemic inflammatory response syndrome presence in patients admitted to intensive care units with acute infection: a Bayesian network approach

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This study was supported by the National Council for Scientific and Technological Development (CNPq), Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ) and by departmental funds from the D’Or Institute for Research and Education.

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Authors and Affiliations




FGZ, FJA and MS participated in study conception, data interpretation and drafting of the manuscript. FGZ and FJA performed the statistical analysis and produced the figures. FGZ, FAB, JIFS and MS led data collection and cleaning. All authors revised the manuscript for important intellectual content and approved the final version of the manuscript.

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Correspondence to Fernando G. Zampieri.

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Conflicts of interest

JIFS and MS are founders and proprietors of Epimed®, a cloud-based solution for ICU performance measurements and benchmarking. The other authors report no conflicts of interest to declare.

Ethical approval

The local ethics committee at the D’Or Institute for Research and Education (Approval Number 334.835) and the Brazilian National Ethics Committee (CAAE 19687113.8.1001.5249) approved the ORCHESTRA study and analyses.

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Zampieri, F.G., Aguiar, F.J., Bozza, F.A. et al. Modulators of systemic inflammatory response syndrome presence in patients admitted to intensive care units with acute infection: a Bayesian network approach. Intensive Care Med 45, 1156–1158 (2019).

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