Validation and comparison of CAM-ICU and ICDSC in mild and moderate traumatic brain injury patients
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Delirium is defined as an acute change or fluctuating mental status and inattention, and either disorganized thinking or altered level of consciousness and has been associated with significant increases in hospital length of stay, long-term cognitive impairment, and mortality [1, 2, 3]. Guidelines recommend routine screening for delirium in ICU patients using a validated tool . Traumatic brain injury (TBI) can induce focal or diffuse brain damage, which may predispose patients to neuropsychiatric complications including delirium as well as complexify its evaluation . The aim of our study was to evaluate the validity and reliability of both the Confusion Assessment Method–Intensive Care Unit (CAM-ICU) and Intensive Care Delirium Screening Checklist (ICDSC) for delirium assessment in patients with mild [Glasgow Coma Scale (GCS 13–15)] or moderate (GCS 9–12) TBI.
KeywordsTraumatic Brain Injury Severe Traumatic Brain Injury Traumatic Brain Injury Patient Richmond Agitation Sedation Scale Moderate Traumatic Brain Injury
We thank our colleagues from Montreal General Hospital: Marc-Alexandre Duceppe, Pharm.D, M.Sc, Audrée Elliot, B.Pharm, M.Sc, Mélissa Para, Pharm.D, M.Sc and Marie-Christine Poirier, Pharm.D, M.Sc for their partnership. We thank Dave Brindamour, B.Pharm, M.Sc, Émilie David, BPharm, M.Sc, Sarah Clairoux, Pharm.D, M.Sc, Paul Murgoi, B.Pharm, M.Sc, Anne-Marie Daigneault, B.Pharm, M.Sc, Isabelle Couture, B.Pharm, M.Sc and Sébastien Dupuis, Pharm.D, M.Sc, for their commitment and implication in this project. We would like to thank the ICU nursing staff of the Hôpital du Sacré-Coeur and Montreal General Hospital for their collaboration and assistance. We thank Anne-Sophie Julien, M.Sc., for the statistical analysis. Finally, we would like to thank Isabelle Racine for her collaboration and the Toronto Western Hospital for allowing us to train with their specialists. Financial support was provided by the Hôpital du Sacré-Coeur de Montréal pharmacy department.
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Conflicts of interest
The authors have no conflict of interest to declare.
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