Severe adenoviral respiratory infection in children
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Viral respiratory infections are a leading cause of illness and hospitalization in young children worldwide. Adenoviral respiratory tract infections occur primarily in infants and young children and can manifest as bronchiolitis, exacerbations of wheezing and asthma, croup, pneumonia and pneumonitis in transplant recipients . We investigated the impact of adenovirus on morbidity and mortality outcomes in children with severe viral respiratory infection.
Following approval by our institutional review board, we performed a retrospective cohort study identifying all patients with laboratory-confirmed adenoviral respiratory infection admitted to the pediatric or cardiac intensive care unit (ICU) at our institution between January 2010 and May 2012. Infection was defined as the identification of adenovirus from a nasopharyngeal or endotracheal specimen by polymerase chain reaction testing.
KeywordsAcute Myeloid Leukemia Respiratory Syncytial Virus Pediatric Intensive Care Unit Cidofovir Croup
All work pertinent to this article was conducted at the Children’s National Medical Center, Washington, DC, USA.
Conflicts of interest
The author has no conflicts of interest or financial disclosures to declare.