Intensive Care Medicine

, Volume 39, Issue 6, pp 1157–1158 | Cite as

Severe adenoviral respiratory infection in children

  • Michael C. SpaederEmail author

Dear Editor,

Viral respiratory infections are a leading cause of illness and hospitalization in young children worldwide. Adenoviral respiratory tract infections occur primarily in infants and young children and can manifest as bronchiolitis, exacerbations of wheezing and asthma, croup, pneumonia and pneumonitis in transplant recipients [1]. We investigated the impact of adenovirus on morbidity and mortality outcomes in children with severe viral respiratory infection.

Following approval by our institutional review board, we performed a retrospective cohort study identifying all patients with laboratory-confirmed adenoviral respiratory infection admitted to the pediatric or cardiac intensive care unit (ICU) at our institution between January 2010 and May 2012. Infection was defined as the identification of adenovirus from a nasopharyngeal or endotracheal specimen by polymerase chain reaction testing.

There were 302 patients with laboratory-confirmed adenoviral respiratory infection...


Acute Myeloid Leukemia Respiratory Syncytial Virus Pediatric Intensive Care Unit Cidofovir Croup 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



All work pertinent to this article was conducted at the Children’s National Medical Center, Washington, DC, USA.

Conflicts of interest

The author has no conflicts of interest or financial disclosures to declare.


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Copyright information

© Springer-Verlag Berlin Heidelberg and ESICM 2013

Authors and Affiliations

  1. 1.Division of Critical Care MedicineChildren’s National Medical CenterWashingtonUSA

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