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Unveiling alveolar recruitment: the fascinating trail between theory and practice

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References

  1. Gattinoni L, Caironi P, Cressoni M, Chiumello D, Ranieri VM, Quintel M, Russo S, Patroniti N, Cornejo R, Bugedo G (2006) Lung recruitment in patients with acute respiratory distress syndrome. N Engl J Med 354:1775–1786

    Article  PubMed  CAS  Google Scholar 

  2. The National Heart, Lung and Blood Institute ARDS Clinical Trials Network (2004) Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med 351:327–336

    Article  Google Scholar 

  3. Villar J, Kacmarek RM, Perez-Mendez L, Aguirre-Jaime A, for the ARIES Network (2006) A high positive end-expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome: a randomized, controlled trial. Crit Care Med 34:1311–1318

    Article  PubMed  Google Scholar 

  4. Gattinoni L, Caironi P, Pelosi P, Goodman LR (2001) What has computed tomography taught us about the acute respiratory distress syndrome? Am J Respir Crit Care Med 164:1701–1711

    PubMed  CAS  Google Scholar 

  5. Lu Q, Constantin JM, Nieszkowska A, Elman M, Vieira S, Rouby JJ (2006) Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure-volume curve. Critical Care 10:R95

    Article  PubMed  Google Scholar 

  6. Richard JC, Maggiore SM, Mercat A (2003) Clinical review: bedside assessment of alveolar recruitment. Critical Care 8:163–169

    Article  PubMed  Google Scholar 

  7. Henzler D, Pelosi P, Dembinski R, Ullmann A, Mahnken AH, Rossaint R, Kuhlen R (2005) Respiratory compliance but not gas exchange correlates with changes in lung aeration after a recruitment manoeuvre; an experimental study in pigs with saline lavage lung injury. Critical Care 9:R471–R482

    Article  PubMed  Google Scholar 

  8. Malbouisson LM, Muller JC, Constantin JM, Lu Q, Puybasset L, Rouby JJ, and the CT scan ARDS study group (2001) Computed tomography assessment of positive end-expiratory pressure-induced alveolar recruitment in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 163:1444–1450

    PubMed  CAS  Google Scholar 

  9. Tusman G, Suarez Sipmann F, Böhm S (2006) Monitoring dead space during recruitment and PEEP titration in an experimental model. Intensive Care Med DOI 10.1007/s00134-006-0371-7

  10. Richard JC, Lebars D, Costes N, Bregeon F, Tourvieille C, Lavenne F, Janier M, Gimenez G, Guerin C (2006) Alveolar recruitment assessed by positron emission tomography during experimental acute lung injury. Intensive Care Med DOI 10.1007/s00134-006-0331-2

  11. Lewis S, Martin CJ (1979) Characteristics of the washout dead space. Respir Physiol 36:51–63

    Article  PubMed  CAS  Google Scholar 

  12. Suter PM, Fairley B, Isenberg MD (1975) Optimum end-expiratory airway pressure in patients with acute pulmonary failure. N Engl J Med 292:284–289

    Article  PubMed  CAS  Google Scholar 

  13. Gattinoni L, Vagginelli F, Carlesso E, Taccone P, Conte V, Chiumello D, Valenza F, Caironi P, Pesenti A, for the Prone-Supine Study Group (2003) Decrease in PaCO2 with prone position is predictive of improved outcome in acute respiratory distress syndrome. Crit Care Med 31:2727–2733

    Article  PubMed  Google Scholar 

  14. West JB, Fowler KT, Hugh-Jones P, O'Donnell TV (1957) Measurement of the ventilation-perfusion ratio inequality in the lung by the analysis of a single expirate. Clin Sci 16:529–547

    PubMed  CAS  Google Scholar 

  15. Meyer M, Mohr M, Schulz H, Piiper J (1990) Sloping alveolar plateaus of CO2, O2, and intravenously infused C2H2 and CHClF2 in the dog. Respir Physiol 81:137–152

    Article  PubMed  CAS  Google Scholar 

  16. Jones HA, Clark RJ, Rhodes CG, Schofield JB, Krausz T, Haslett C (1994) In vivo measurement of neutrophil activity in experimental lung inflammation. Am J Respir Crit Care Med 149:1635–1639

    PubMed  CAS  Google Scholar 

  17. Chen DL, Ferkol TW, Mintun MA, Pittman JE, Rosenbluth DB, Schuster DP (2006) Quantifying pulmonary inflammation in cystic fibrosis with positron emission tomography. Am J Respir Crit Care Med 173:1363–1369

    Article  PubMed  Google Scholar 

  18. Chen DL, Rosenbluth DB, Mintun MA, Schuster DP (2006) FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin. J Appl Physiol 100:1602–1609

    Article  PubMed  CAS  Google Scholar 

  19. Hedenstierna G, Hammond M, Mathieu-Costello O, Wagner PD (2000) Functional lung unit in the pig. Respir Physiol 120:139–149

    Article  PubMed  CAS  Google Scholar 

  20. Tucker A, Rhodes J (2001) Role of vascular smooth muscle in the development of high altitude pulmonary hypertension: an interspecies evaluation. High Alt Med Biol 2:173–189

    Article  PubMed  CAS  Google Scholar 

  21. Maggiorini M, Melot C, Gilbert E, Vermeulen F, Naeije R (1998) Pulmonary vascular resistance in dogs and minipigs: effects of hypoxia and inhaled nitric oxide. Respir Physiol 111:213–222

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Sektion Anästhesiologische Pathophysiologie und Verfahrensentwicklung, Universitätsklinik für Anästhesiologie, Universität Ulm, Parkstrasse 11, 89070, Ulm, Germany

    Enrico Calzia & Peter Radermacher

  2. Klinik für Anästhesiologie, Universität Regensburg, Regensburg, Germany

    Thomas Bein

Authors
  1. Enrico Calzia
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  2. Peter Radermacher
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  3. Thomas Bein
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Corresponding author

Correspondence to Enrico Calzia.

Additional information

This editorial refers to the articles available at: http://dx.doi.org/10.1007/s00134-006-0331-2 and http://dx.doi.org/10.1007/s00134-006-0371-7

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Calzia, E., Radermacher, P. & Bein, T. Unveiling alveolar recruitment: the fascinating trail between theory and practice. Intensive Care Med 32, 1686–1688 (2006). https://doi.org/10.1007/s00134-006-0372-6

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