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Safety of endotoxin challenge in healthy volunteers: bradycardia

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References

  1. Fiuza C, Suffredini AF (2001) Human models of innate immunity: local and systemic inflammatory responses. J Endotoxin Res 7:385–388

    Google Scholar 

  2. Martich GD, Boujoukos AJ, Suffredini AF (1993) Response of man to endotoxin. Immunobiology 187:403–416

    CAS  PubMed  Google Scholar 

  3. Jilma B, Marsik C, Mayr F, Graninger MT, Taylor FB Jr, Ribel MC, Erhardtsen E, Handler S, Eichler HG (2002) Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans. Clin Pharmacol Ther 72:403–410

    Google Scholar 

  4. van Eijk LT, Pickkers P, Smits P, Bouw MP, van der Hoeven JG (2004) Severe vagal response after endotoxin administration in humans. Intensive Care Med (E-pub ahead of publication)

  5. Williams WV, Fullerton T, Fox JC, Enslin MB, Murray L, Jorkasky D (2000) Asystole following endotoxin administration. J Endotoxin Res 6:303–306

    CAS  PubMed  Google Scholar 

  6. Pernerstorfer T, Schmid R, Bieglmayer C, Eichler HG, Kapiotis S, Jilma B (1999) Acetaminophen has greater antipyretic efficacy than aspirin in endotoxemia: a randomized, double-blind, placebo-controlled trial. Clin Pharmacol Ther 66:51–57

    Google Scholar 

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Correspondence to Bernd Jilma.

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Jilma, B. Safety of endotoxin challenge in healthy volunteers: bradycardia. Intensive Care Med 31, 496 (2005). https://doi.org/10.1007/s00134-005-2562-z

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