References
Fiuza C, Suffredini AF (2001) Human models of innate immunity: local and systemic inflammatory responses. J Endotoxin Res 7:385–388
Martich GD, Boujoukos AJ, Suffredini AF (1993) Response of man to endotoxin. Immunobiology 187:403–416
Jilma B, Marsik C, Mayr F, Graninger MT, Taylor FB Jr, Ribel MC, Erhardtsen E, Handler S, Eichler HG (2002) Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans. Clin Pharmacol Ther 72:403–410
van Eijk LT, Pickkers P, Smits P, Bouw MP, van der Hoeven JG (2004) Severe vagal response after endotoxin administration in humans. Intensive Care Med (E-pub ahead of publication)
Williams WV, Fullerton T, Fox JC, Enslin MB, Murray L, Jorkasky D (2000) Asystole following endotoxin administration. J Endotoxin Res 6:303–306
Pernerstorfer T, Schmid R, Bieglmayer C, Eichler HG, Kapiotis S, Jilma B (1999) Acetaminophen has greater antipyretic efficacy than aspirin in endotoxemia: a randomized, double-blind, placebo-controlled trial. Clin Pharmacol Ther 66:51–57
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Jilma, B. Safety of endotoxin challenge in healthy volunteers: bradycardia. Intensive Care Med 31, 496 (2005). https://doi.org/10.1007/s00134-005-2562-z
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00134-005-2562-z