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To consent or not to consent, that is (not) the (sole) question.

“And there is nothing new under the sun”. Kohelet (also known as Ecclesiastes), 1:9. Bible

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References

  1. Beecher HK (1966) Ethics and clinical research. N Engl J Med 274:1354–1360

    Article  CAS  Google Scholar 

  2. Lemaire F (2003) Suspension of the NIH ARDS Network fluids and catheters treatment trial. Intensive Care Med 29:1361–1363

    Article  Google Scholar 

  3. Grunberg SM, Cefalu WT (2003) The integral role of clinical research in clinical care. N Engl J Med 348:1386–1388

    Article  Google Scholar 

  4. Miller FG, Rosenstein DL (2003) The therapeutic orientation to clinical trials. N Engl J Med 348:1383–1386

    Article  Google Scholar 

  5. Luce JM (2003) Is the concept of informed consent applicable to clinical research involving critically ill patients? Crit Care Med 31:S153–S160

    Article  Google Scholar 

  6. Marx K, Engels F (1848) The communist manifesto

  7. Singer EA, Mullner M (2002) Implications of the EU directive on clinical trials for emergency medicine. BMJ 324:1169–1170

    Article  Google Scholar 

  8. Lemaire FJ (2003) A European Directive for clinical research. Intensive Care Med 18:18

    Google Scholar 

  9. Lemaire F (2003) A waiver of consent for intensive care research? Intensive Care Med (http://dx.doi.org/10.1007/s00134-003-2063-x)

  10. Annane D, Outin H, Fisch C, Bellissant E (2003) Informed consent for randomised controlled trials in critically ill patients: the case of septic shock. Intensive Care Med (http://dx.doi.org/10.1007/s00134-003-2065-8)

    Google Scholar 

  11. Evidence-based medicine working group (1992) Evidence-based medicine. A new approach to teaching the practice of medicine. JAMA 268:2420–2425

    Article  Google Scholar 

  12. Cook, DJ, Guyatt GH, Laupacis A, Sackett DL, Goldberg RJ(1995) Clinical recommendations using levels of evidence for antithrombotic agents. Chest 108:227S-230S

    Article  CAS  Google Scholar 

  13. Tobin MJ (2003) The role of a journal in a scientific controversy. Am J Respir Crit Care Med 168:511–515

    Article  Google Scholar 

  14. Dreyfuss, D, Saumon G (2002) Evidence-based medicine or fuzzy logic. What is best for ARDS management? Intensive Care Med 28:230–234

    Article  Google Scholar 

  15. Paasche-Orlow MK, Taylor HA, Brancati FL (2003) Readability standards for informed-consent forms as compared with actual readability. N Engl J Med 348721–726

  16. Pochard F, Azoulay E, Chevret S, Lemaire F, Hubert P, Canoui P, Grassin M, Zitoun R, Le Gall JR, Dhainaut JF, Schlemmer B, French FAMIREA Group (2001) Symptoms of anxiety and depression in family members of intensive care unit patients: ethical hypothesis regarding decision-making capacity. Crit Care Med 29:1893–1897

    Article  CAS  Google Scholar 

  17. Faisy C, Guerot E, Diehl JL, Iftimovici E, JY Fagon (2003), Clinically significant gastrointestinal bleeding in critically ill patients with and without stress-ulcer prophylaxis. Intensive Care Med 29:1306–1313

    Article  Google Scholar 

  18. Concato J, Shah N, Horwitz RI (2000) Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med 342:1887–1892

    Article  CAS  Google Scholar 

  19. Benson K, Hartz AJ (2000) A comparison of observational studies and randomized, controlled trials. N Engl J Med 342:1878–1886

    Article  CAS  Google Scholar 

  20. Zelen M (1979) A new design for randomized clinical trials. N Engl J Med 300:1242–1245

    Article  CAS  Google Scholar 

  21. Truog RD, et al (1999) Is informed consent always necessary for randomized, controlled trials? N Engl J Med 340:804–807

    Article  CAS  Google Scholar 

  22. Freeman BD, et al (2001) Safeguarding patients in clinical trials with high mortality rates. Am J Respir Crit Care Med 164:190–192

    Article  CAS  Google Scholar 

  23. Mello MM, Studdert DM, Brennan TA (2003) The rise of litigation in human subjects research. Ann Intern Med 139:40–45

    Article  Google Scholar 

  24. Clifton GL, Knudson P, McDonald M (2002) Waiver of consent in studies of acute brain injury. J Neurotrauma 19:1121–1126

    Article  Google Scholar 

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Authors and Affiliations

  1. Hôpital Louis Mourier, Colombes and Assistance Publique—Hôpitaux de Paris, Paris, France

    Didier Dreyfuss

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  1. Didier Dreyfuss
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Correspondence to Didier Dreyfuss.

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Dreyfuss, D. To consent or not to consent, that is (not) the (sole) question.. Intensive Care Med 30, 180–182 (2004). https://doi.org/10.1007/s00134-003-2064-9

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  • DOI: https://doi.org/10.1007/s00134-003-2064-9

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