Skip to main content
Log in

Clinical studies in severe traumatic brain injury: a controversial issue

  • Editorial
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Ghajar J, Hariri RJ, Narayan RK, Iacono LA, Firlik K, Patterson RH (1995) Survey of critical care management of comatose, head-injured patients in the United States. Crit Care Med 23:560–567

    Article  CAS  PubMed  Google Scholar 

  2. Chesnut RM, Marshall LF, Klauber MR, Blunt BA, Baldwin N, Eisenberg HM, et al (1993) The role of secondary brain injury in determining outcome from severe head injury. J Trauma 34: 216–222

    Article  CAS  PubMed  Google Scholar 

  3. Lundberg N (1960) continuous recording and control of ventricular fluid pressure in neurosurgical practice. Acta Psychiatr Neurol Scand 36: 1–193

    CAS  Google Scholar 

  4. Murray GD, Teasdale GM, Braakman R, Cohadon F, Dearden M, Iannotti F, et al (1999) The European Brain Injury Consortium Survey of Head Injuries. Acta Neurochir (Wien) 141:223–236

    Article  CAS  Google Scholar 

  5. Patel HC, Menon DK, Tebbs S, Hawker R, Hutchinson PJ, Kirkpatrick PJ (2002) Specialist neurocritical care and outcome from head injury. Intensive Care Med. http://dx.doi.org/ 10.1007/s00134-002-1235-4

  6. Rosner MJ, Rosner SD, Johnson AH (1995) Cerebral perfusion pressure: management protocol and clinical results. J Neurosurg 83:949–962

    Article  CAS  PubMed  Google Scholar 

  7. Asgeirsson B, Grände PO, Nordström CH (1994) A new therapy of posttrauma brain oedema based on haemodynamic principles for brain volume regulation. Intensive Care Med 20: 260–267

    Article  CAS  PubMed  Google Scholar 

  8. Naredi S, Edén E, Zäll S, Stephensen H, Rydenhag B (1998) A standardized neurosurgical/neurointensive therapy directed toward vasogenic edema after severe traumatic brain injury: clinical results. Intensive Care Med 24:446–451

    Article  CAS  PubMed  Google Scholar 

  9. Clifton GL, Miller ER, Choi SC, Levin HS, McCauley S, Smith KR (2001) Lack of effect of induction of hypothermia after acute brain injury. N Engl J Med 344. 556–563

    Article  CAS  PubMed  Google Scholar 

  10. Maas AIR, Steyerberg EW, Murray GD, Bullock R, Baethmann A, Marshall LF, Teasdale GM (1999) Why have recent trials of neuroprotective agents in head injury failed to show convincing efficacy? A pragmatic analysis and theoretical considerations. Neurosurgery 44:1286–1289

    PubMed  Google Scholar 

  11. Brain Trauma Foundation, American Association of Neurological Surgeons (2000) The joint section on Neurotrauma and Critical Care. Guidelines for cerebral perfusion pressure. J Neurotrauma 17:507–511

    Article  Google Scholar 

  12. Maas A, Dearden M, Teasdale GM, et al (1997) EBIC guidelines for management of severe head injury in adults. Acta Neurochir (Wien) 139:286–294

    Article  CAS  Google Scholar 

  13. Grände P-O, Asgeirsson B, and Nordström CH (1997) Physiological principles for volume regulation of a tissue enclosed in a rigid shell with application to the injured brain. J Trauma 42: S23–S31

    Article  PubMed  Google Scholar 

  14. Naredi S, Olivecrona M, Lindgren C, Östlund A-L, Grände P-O, Koskinen LOD (2001) An outcome study of severe traumatic head injury using the “Lund therapy” with low-dose prostacyclin. Acta Anaesthesiol Scand 45: 402–406

    Article  CAS  PubMed  Google Scholar 

  15. Robertson CS, Valadka AB, Hannay HJ, Contant CF, Gopinath SP, Cormio M, et al (1999) Prevention of secondary ischemic insults after severe head injury. Crit Care Med 10:2068–2095

    Google Scholar 

  16. Juul N, Morris GF, Marshall SB, Marshall LF (2000) Intracranial hypertension and cerebral perfusion pressure: influence on neurological deterioration and outcome in severe head injury. The Executive Committee of the International Selfotel Trial. J Neurosurg 92:1–6

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Per-Olof Grände.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grände, PO., Naredi, S. Clinical studies in severe traumatic brain injury: a controversial issue. Intensive Care Med 28, 529–531 (2002). https://doi.org/10.1007/s00134-002-1236-3

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-002-1236-3

Navigation