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Spätkomplikationen nach neo-/adjuvanter Strahlentherapie und Resektion von Sarkomen der Extremitäten oder des Beckens/Retroperitoneums

Ansätze zur Prävention

Late complications following neo-/adjuvant radiotherapy and surgery for sarcomas of the extremities or pelvis/retroperitoneum

Preventative measures

  • 18 Accesses


Die Strahlentherapie besitzt im multimodalen Therapiekonzept von Sarkomen der Extremitäten oder des Beckens/Retroperitoneums einen festen Stellenwert. Die Strahlentherapie kann vor oder im Anschluss an die geplante Operation erfolgen. Neue Bestrahlungstechniken, wie z. B. die intensitätsmodulierte Strahlentherapie mit hochenergetischen Photonen oder die Protonentherapie, tragen zu geringeren akuten und späten Nebenwirkungen bei. In diesem Übersichtsartikel sind diese Ansätze dargestellt.


Radiotherapy is one of the pillars in the multimodal therapy of sarcomas of the extremities or pelvis/retroperitoneum. It can be delivered prior to or following surgery. Novel radiation techniques, such as intensity-modulated radiotherapy using high-energy photons or protons, contribute to the reduction of acute and late toxicities. This review article summarizes these concepts.

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American Society of Clinical Oncology


Bildgeführte Strahlentherapie


Intensitätsmodulierte Bestrahlung


Intraoperative Brachytherapie


Intraoperative Radiotherapie




„Relative biological effectiveness“




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Correspondence to Dr. C. Jentsch.

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C. Jentsch, C. Hofbauer, S. Makocki und E. Troost geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Jentsch, C., Hofbauer, C., Makocki, S. et al. Spätkomplikationen nach neo-/adjuvanter Strahlentherapie und Resektion von Sarkomen der Extremitäten oder des Beckens/Retroperitoneums. Orthopäde 49, 177–182 (2020). https://doi.org/10.1007/s00132-020-03881-0

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  • Extremitäten
  • Photonentherapie
  • Protonentherapie
  • Radiotherapie, intensitätsmodulierte
  • Weichgewebstumore


  • Limb
  • Photon beam therapy
  • Proton beam therapy
  • Radiotherapy, intensity-modulated
  • Soft tissue neoplasms