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Bösartige Weichgewebsgeschwülste

Resektion und plastische Wiederherstellung

Soft tissue sarcoma

Resection and plastic reconstruction

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Zusammenfassung

Die operative Entfernung mit einem Sicherheitsabstand von 1–2 cm stellt die Basis der multidisziplinären Versorgung von Weichgewebssarkomen des Rumpfes und der Extremitäten dar. Bei Tumoren mit hoher biologischer Aktivität (Grading 2/3) ist die perioperative Radiatio/Chemotherapie unter Studienbedingungen indiziert. Für periphere Lokalisationen oder Komplikationen werden im Tumorboard zusätzliche Möglichkeiten wie die hypertherme Perfusion mit Tumornekrosefaktor α oder das gesamte Spektrum der plastischen Wiederherstellung einbezogen. Grundsätzlich sollten Patienten mit Weichgewebssarkomen in „high volume“-Zentren versorgt werden.

Abstract

Adequate surgical removal of soft tissue sarcomas of the trunk and extremities employing safety margins of 1–2 cm is the accepted basis of multidisciplinary treatment. In cases of high risk tumors (grades G2/G3) the tumor board decision should include radiochemotherapy under study conditions. Difficult peripheral locations or perioperative complications require additional techniques, such as hyperthermic perfusion with tumor necrosis factor alpha or the complete spectrum of reconstructive plastic procedures. Patients with soft tissue sarcoma of the trunk or of the extremities should always be referred to high volume centers.

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Authors and Affiliations

  1. Handchirurgiezentrum, Operatives Referenzzentrum für Weichgewebssarkome, Klinik für Plastische Chirurgie und Schwerbrandverletzte, BG-Universitätsklinik Bergmannsheil, Ruhr-Universität Bochum, Bürkle de la Camp Platz 1, 44799, Bochum, Deutschland

    H.U. Steinau, L. Steinsträsser, J. Hauser, D. Tilkorn & A. Daigeler

  2. Institut für Pathologie, BG-Universitätsklinik Bergmannsheil, Ruhr-Universität Bochum, Bochum, Deutschland

    I. Stricker 

Authors
  1. H.U. Steinau
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  2. L. Steinsträsser
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  3. J. Hauser
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  4. D. Tilkorn
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  5. I. Stricker 
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  6. A. Daigeler
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Correspondence to H.U. Steinau.

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Steinau, H., Steinsträsser, L., Hauser, J. et al. Bösartige Weichgewebsgeschwülste. Orthopäde 41, 165–176 (2012). https://doi.org/10.1007/s00132-011-1876-5

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  • DOI: https://doi.org/10.1007/s00132-011-1876-5

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