Zusammenfassung
Zur Behandlung krebsbedingter Knochenmetastasen werden viele perkutane bildgeführte ablative Techniken eingesetzt. Sie werden in der palliativen und kurativen Therapie sowohl bei gutartigem als auch bei malignem Knochenkrebs immer wichtiger.
Dieser Artikel fasst die Prinzipien der Radiofrequenzablation und unsere Erfahrungen damit kurz zusammen. Dabei geht es auch um ihren Einsatz in Verbindung mit operativen Techniken. Weitere minimal-invasive Techniken wie Kryoablation und Osteoplastik zur Behandlung von Knochenmetastasen werden vorgestellt.
Abstract
Many percutaneous image-guided ablative techniques have been used in the treatment of cancer-related bone metastases. These techniques are rapidly becoming a focus in the palliative and curative treatment of patients with both benign and malignant bone cancer.
In this article we will briefly review the principles of radiofrequency ablation and our experience with this technique, including its use in combination with surgery; we will also discuss other minimally invasive techniques such as cryoablation and osteoplasty in the treatment of bone metastases.
Literatur
Sironi S, Livraghi T, Angeli E et al (1993) Small hepatocellular carcinoma: MR follow-up of treatment with percutaneous ethanol injection. Radiology 187: 119–123
Allgaier HP, Deibert P, Zuber I et al (1999) Percutaneous radiofrequency interstitial thermal ablation of small hepatocellular carcinoma. Lancet 353: 1676–1677
Woertler K, Vestring T, Boettner F et al (2001) Osteoid osteoma: CT-guided percutaneous radiofrequency ablation and follow-up in 47 patients. J Vasc Interv Radiol 12: 717–722
Grönemeyer DH, Schirp S, Gevargez A (2002) Image-guided radiofrequency ablation of spinal tumors: preliminary experience with an expandable array electrode. Cancer J 8: 33–39
Goetz MP, Callstrom MR, Charboneau JW et al (2004) Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study. J Clin Oncol 22: 300–306
Galibert P, Deramond H, Rosat P, Le Gars D (1987) Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie 33: 166–168
Cotten A, Deprez X, Migaud H et al (1995) Malignant acetabular osteolyses: percutaneous injection of acrylic bone cement. Radiology 197: 307–310
Marcy PY, Palussière J, Descamps B et al (2000) Percutaneous cementoplasty for pelvic bone metastasis. Support Care Cancer 8: 500–503
Harty JA, Brennan D, Eustace S, O’Byrne J (2003) Percutaneous cementoplasty of acetabular bony metastasis. Surgeon 1: 48–50
Kelekis A, Lovblad KO, Mehdizade A et al (2005) Pelvic osteoplasty in osteolytic metastases: technical approach under fluoroscopic guidance and early clinical results. J Vasc Interv Radiol 16: 81–88
Masala S, Roselli M, Massari F et al (2004) Radiofrequency heat ablation and vertebroplasty in the treatment of neoplastic vertebral body fractures. Anticancer Res 24: 3129–3133
Nakatsuka A, Yamakado K, Maeda M et al (2004) Radiofrequency ablation combined with bone cement injection for the treatment of bone malignancies. J Vasc Interv Radiol 15: 707–712
Kastler B, Jacamon M, Aubry S et al (2007) Combined bipolar radiofrequency and cementoplasty of bone metastases. J Radiol 88: 1242–1247
Gangi A, Kastler B, Klinkert A, Dietemann JL (1994) Injection of alcohol into bone metastases under CT guidance. J Comput Assist Tomogr 18: 932–935
Monchik JM, Donatini G, Iannuccilli J, Dupuy DE (2006) Radiofrequency ablation and percutaneous ethanol injection treatment for recurrent local and distant well-differentiated thyroid carcinoma. Ann Surg 244: 296–304
Schaefer O, Lohrmann C, Herling M et al (2002) Combined radiofrequency thermal ablation and percutaneous cementoplasty treatment of a pathologic fracture. J Vasc Interv Radiol 13: 1047–1050
Glaiberman CB, Brown DB (2004) Reversible neuropathy caused by overuse following radiofrequency ablation of metastatic pelvic lesions. J Vasc Interv Radiol 15: 1307–1310
Gangi A, Dietemann JL, Schultz A et al (1996) Interventional radiologic procedures with CT guidance in cancer pain management. Radiographics 16: 1289–1304
Cotten A, Demondion X, Boutry N et al (1999) Therapeutic percutaneous injections in the treatment of malignant acetabular osteolyses. Radiographics 19: 647–653
Callstrom MR, Atwell TD, Charboneau JW et al (2006) Painful metastases involving bone: percutaneous image-guided cryoablation–prospective trial interim analysis. Radiology 241: 572–580
Atwell TD, Farrell MA, Callstrom MR et al (2007) Percutaneous cryoablation of 40 solid renal tumors with US guidance and CT monitoring: initial experience. Radiology 243: 276–283
Interessenkonflikt
Keine Angaben
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Capanna, R., De Biase, P. & Sensi, L. Minimal-invasive Techniken zur Behandlung metastasierter Karzinome. Orthopäde 38, 343–347 (2009). https://doi.org/10.1007/s00132-008-1378-2
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00132-008-1378-2