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Diagnostik und Therapie der Osteogenesis imperfecta

Diagnosis and therapy of osteogenesis imperfecta

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An Erratum to this article was published on 30 January 2008


Die Osteogenesis imperfecta (OI) ist eine angeborene Erkrankung des Bindegewebes mit einer Häufigkeit bis zu 1/30.000. Die Patienten leiden v. a. unter Deformitäten und Frakturen, viele erreichen nie die Gehfähigkeit. Die Therapie umfasst konservative, medikamentöse und operative Verfahren, die im Folgenden dargestellt werden.


Osteogenesis imperfecta (OI) is a congenital connective tissue disorder with an incidence of up to 1:30,000. Patients suffer from deformities and fractures, and many of them never reach ambulation. The therapy consists of conservative, medicamentous and operative procedures that are described in this article.

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Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Correspondence to A. Meurer.

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Ein Erratum zu diesem Beitrag ist unter 10.1007/s00132-008-1211-y zu finden.

An erratum to this article can be found at

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Meurer, A. Diagnostik und Therapie der Osteogenesis imperfecta. Orthopäde 37, 17–23 (2008).

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