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Operative Therapie des Endometriumkarzinoms

Surgical treatment of endometrial cancer

  • Leitthema
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Zusammenfassung

Im Juli 2022 ist mit der Version 2.0 das erste Update der deutschen interdisziplinären S3-Leitlinie für die Diagnostik, Therapie und Nachsorge der Patientinnen mit Endometriumkarzinom, gefördert durch das Leitlinienprogramm Onkologie erschienen. Dieser Artikel ist die Zusammenfassung des Kap. 6: „Operative Therapie“. Wesentliche Neuerungen gegenüber der Version 1.0 sind die Einführung der molekularen Klassifikation zur Risikoabschätzung und damit gezielteren individualisierten Therapie, die stadienbasierte Sentinellymphknotenbiopsie sowie die Option der neoadjuvanten Chemotherapie bei primär inoperablen Endometriumkarzinomen.

Abstract

In July 2022, the first update (Version 2.0) of the German S3 guideline on the diagnosis, treatment and follow-up of patients with endometrial cancer was published, supported by the Leitlinienprogramm Onkologie (Oncology Guideline Program). This article is the summary of Chap. 6: “Surgical Treatment”. Relevant innovations compared to version 1.0 include the introduction of molecular classification and sentinel node biopsy, as well as the option of neoadjuvant chemotherapy for advanced cases where primary cytoreductive surgery is not possible.

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Authors and Affiliations

  1. Klinik für Gynäkologie und Geburtshilfe, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland

    G. Emons & S. Erdogan

  2. Universitätsfrauenklinik Tübingen, Tübingen, Deutschland

    S. Y. Brucker

  3. Landesfrauenklinik Helios Universitätsklinikum Wuppertal, Wuppertal, Deutschland

    M. C. Fleisch

  4. Universitätsklinik für Frauenheilkunde, Inselspital Bern, Bern, Schweiz

    M. Mueller

  5. Universitätsfrauenklinik Freiburg, Freiburg, Deutschland

    E. Juhasz-Böss

  6. Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Münster, Münster, Deutschland

    L. Kiesel

  7. Klinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin, Universitätsklinikum Jena, Jena, Deutschland

    I. B. Runnebaum

  8. Frauenklinik, Helios Klinikum Krefeld, Krefeld, Deutschland

    M. Friedrich

  9. Universitätsfrauenklinik Bonn, Bonn, Deutschland

    A. Mustea

  10. Frauenklinik, Universitätsklinikum Erlangen, Erlangen, Deutschland

    M. W. Beckmann

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  1. G. Emons
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  2. S. Y. Brucker
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  3. M. C. Fleisch
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  4. M. Mueller
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Correspondence to G. Emons.

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Interessenkonflikt

G. Emons, S.Y. Brucker, M.C. Fleisch, M. Mueller, E. Juhasz-Böss, L. Kiesel, I.B. Runnebaum, M. Friedrich, A. Mustea, S. Erdogan und M.W. Beckmann geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Günter Emons, Göttingen

Teile dieses Beitrags entstammen wörtlich aus dem Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft, Deutsche Krebshilfe, AWMF) (2022) Diagnostik, Therapie und Nachsorge der Patientinnen mit Endometriumkarzinom [23].

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Emons, G., Brucker, S.Y., Fleisch, M.C. et al. Operative Therapie des Endometriumkarzinoms. Gynäkologie 55, 493–500 (2022). https://doi.org/10.1007/s00129-022-04958-x

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  • DOI: https://doi.org/10.1007/s00129-022-04958-x

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