Skip to main content
Log in

Sentineltechnik mit ICG in der Gynäkologie

Literaturübersicht und eigene Erfahrungen

Sentinel node technique with ICG in gynecology

Literature review and own experiences

  • Gynäkologie aktuell
  • Published:
Der Gynäkologe Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1

Literatur

  1. Abu-Rustum NR (2014) Update on sentinel node mapping in uterine cancer: 10-year experience at Memorial Sloan-Kettering Cancer Center. J Obstet Gynaecol Res 40:327–334

    Article  Google Scholar 

  2. Brincat MR, Muscat Baron Y (2017) Sentinel lymph node biopsy in the management of vulvar carcinoma: an evidence-based insight. Int J Gynecol Cancer 27:1769–1773

    Article  Google Scholar 

  3. Buda A, Papadia A, Zapardiel I et al (2016) From conventional Radiotracer Tc-99(m) with blue dye to Indocyanine green fluorescence: a comparison of methods towards optimization of sentinel lymph node mapping in early stage cervical cancer for a laparoscopic approach. Ann Surg Oncol 23:2959–2965

    Article  Google Scholar 

  4. Buda A, Passoni P, Corrado G et al (2017) Near-infrared fluorescence-guided sentinel node mapping of the ovary with Indocyanine green in a minimally invasive setting: a feasible study. J Minim Invasive Gynecol 24:165–170

    Article  Google Scholar 

  5. Buderath P, Rusch P, Kimmig R (2019) Kompartmentbasierte Chirurgie und Sentinel-Konzept beim Endometriumkarzinom: der Essener Weg. Gynäkologe 52:538–541

    Article  Google Scholar 

  6. Burger MP, Hollema H, Emanuels AG et al (1995) The importance of the groin node status for the survival of T1 and T2 vulval carcinoma patients. Gynecol Oncol 57:327–334

    Article  CAS  Google Scholar 

  7. Canlorbe G, Rouzier R, Bendifallah S et al (2012) Impact of sentinel node technique on the survival in patients with vulvar cancer: analysis of the Surveillance, Epidemiology, and End Results (SEER) database. Gynecol Obstet Fertil 40:647–651

    Article  CAS  Google Scholar 

  8. Cibula D, Oonk MH, Abu-Rustum NR (2015) Sentinel lymph node biopsy in the management of gynecologic cancer. Curr Opin Obstet Gynecol 27:66–72

    Article  Google Scholar 

  9. Cormier B, Diaz JP, Shih K et al (2011) Establishing a sentinel lymph node mapping algorithm for the treatment of early cervical cancer. Gynecol Oncol 122:275–280

    Article  Google Scholar 

  10. Frumovitz M, Plante M, Lee PS et al (2018) Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial. Lancet Oncol 19:1394–1403

    Article  Google Scholar 

  11. Gezer S, Duman Ozturk S, Hekimsoy T et al (2020) Cervical versus endometrial injection for sentinel lymph node detection in endometrial cancer: a randomized clinical trial. Int J Gynecol Cancer. https://doi.org/10.1136/ijgc-2019-000860

    Article  PubMed  Google Scholar 

  12. Hassanzade M, Attaran M, Treglia G et al (2013) Lymphatic mapping and sentinel node biopsy in squamous cell carcinoma of the vulva: systematic review and meta-analysis of the literature. Gynecol Oncol 130:237–245

    Article  Google Scholar 

  13. Hassanzadeh M, Hosseini Farahabadi E, Yousefi Z et al (2016) Lymphatic mapping and sentinel node biopsy in ovarian tumors: a study using intra-operative Tc-99m-Phytate and lymphoscintigraphy imaging. J Ovarian Res 9:55

    Article  Google Scholar 

  14. Holloway RW, Abu-Rustum NR, Backes FJ et al (2017) Sentinel lymph node mapping and staging in endometrial cancer: a Society of Gynecologic Oncology literature review with consensus recommendations. Gynecol Oncol 146:405–415

    Article  Google Scholar 

  15. How JA, O’farrell P, Amajoud Z et al (2018) Sentinel lymph node mapping in endometrial cancer: a systematic review and meta-analysis. Minerva Ginecol 70:194–214

    PubMed  Google Scholar 

  16. Hutteman M, Van Der Vorst JR, Gaarenstroom KN et al (2012) Optimization of near-infrared fluorescent sentinel lymph node mapping for vulvar cancer. Am J Obstet Gynecol 206:89e1–89e5

    Article  Google Scholar 

  17. Khoury-Collado F, Clair StC, Abu-Rustum NR (2016) Sentinel lymph node mapping in endometrial cancer: an update. Oncologist 21:461–466

    Article  CAS  Google Scholar 

  18. Kimmig R, Buderath P, Rusch P et al (2017) Technique of ICG-guided targeted compartmental pelvic lymphadenectomy (TCL) combined with pelvic peritoneal mesometrial resection (PMMR) for locoregional control of endometrial cancer—A proposal. Gynecol Oncol Rep 20:125–126

    Article  Google Scholar 

  19. Kimmig R, Buderath P, Rusch P et al (2017) Early ovarian cancer surgery with indocyanine-green-guided targeted compartmental lymphadenectomy (TCL, pelvic part). J Gynecol Oncol 28:e68

    Article  Google Scholar 

  20. Kleppe M, Brans B, Van Gorp T et al (2014) The detection of sentinel nodes in ovarian cancer: a feasibility study. J Nucl Med 55:1799–1804

    Article  Google Scholar 

  21. Kleppe M, Wang T, Van Gorp T et al (2011) Lymph node metastasis in stages I and II ovarian cancer: a review. Gynecol Oncol 123:610–614

    Article  CAS  Google Scholar 

  22. Lecuru F, Mathevet P, Querleu D et al (2011) Bilateral negative sentinel nodes accurately predict absence of lymph node metastasis in early cervical cancer: results of the SENTICOL study. J Clin Oncol 29:1686–1691

    Article  Google Scholar 

  23. Lecuru FR, Mccormack M, Hillemanns P et al (2019) SENTICOL III: an international validation study of sentinel node biopsy in early cervical cancer. A GINECO, ENGOT, GCIG and multicenter study. Int J Gynecol Cancer 29:829–834

    Article  Google Scholar 

  24. Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft DK, Awmf) (2018) Diagnostik, Therapie und Nachsorge der Patientinnen mit Endometriumkarzinom, Kurzversion 1.0, 2018, AWMF Registernummer: 032/034-OL. http://www.leitlinienprogramm-onkologie.de/leitlinien/endometriumkarzinom/. Zugegriffen: 19. Nov. 2018

  25. Mahner S, Jueckstock J, Hilpert F, Neuser P, Harter P, de Gregorio N et al (2015) Adjuvant therapy in lymph node-positive vulvar cancer: the AGO-CaRE-1 study. J Natl Cancer Inst. https://doi.org/10.1093/jnci/dju426

    Article  PubMed  PubMed Central  Google Scholar 

  26. Melamed A, Ramirez PT (2020) Changing treatment landscape for early cervical cancer: outcomes reported with minimally invasive surgery compared with an open approach. Curr Opin Obstet Gynecol 32:22–27

    Article  Google Scholar 

  27. Morton DL, Wen DR, Wong JH et al (1992) Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 127:392–399

    Article  CAS  Google Scholar 

  28. Negishi H, Takeda M, Fujimoto T et al (2004) Lymphatic mapping and sentinel node identification as related to the primary sites of lymph node metastasis in early stage ovarian cancer. Gynecol Oncol 94:161–166

    Article  Google Scholar 

  29. Nyberg RH, Korkola P, Maenpaa J (2011) Ovarian sentinel node: is it feasible? Int J Gynecol Cancer 21:568–572

    Article  Google Scholar 

  30. Nyberg RH, Korkola P, Maenpaa JU (2017) Sentinel node and ovarian tumors: a series of 20 patients. Int J Gynecol Cancer 27:684–689

    Article  Google Scholar 

  31. Ramirez PTMF, Parejab R, Lopezc A, Vieirad MA, Ribeiroe R (2018) Phase III randomized trial of laparoscopic or robotic versus abdominal radical hysterectomy in patients with early-stage cervical cancer: LACC Trial. Abstract presented at the 49th Annual Meeting of the Society of Gynecologic Oncology.

    Book  Google Scholar 

  32. Richard SD, Krivak TC, Castleberry A et al (2008) Survival for stage IB cervical cancer with positive lymph node involvement: a comparison of completed vs. abandoned radical hysterectomy. Gynecol Oncol 109:43–48

    Article  Google Scholar 

  33. Rossi EC, Kowalski LD, Scalici J et al (2017) A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study. Lancet Oncol 18:384–392

    Article  Google Scholar 

  34. Sahraoui S, Bouras N, Acharki A et al (2002) Adenocarcinoma of the cervix uteri: a retrospective study of 83 cases. Gynecol Obstet Fertil 30:291–298

    Article  CAS  Google Scholar 

  35. Salvo G, Ramirez PT, Levenback CF et al (2017) Sensitivity and negative predictive value for sentinel lymph node biopsy in women with early-stage cervical cancer. Gynecol Oncol 145:96–101

    Article  Google Scholar 

  36. Schnurch HG, Ackermann S, Alt CD et al (2016) Diagnosis, therapy and follow-up care of vulvar cancer and its precursors. Guideline of the DGGG and DKG (S2k-level, AWMF registry number 015/059, november 2015. Geburtshilfe Frauenheilkd 76:1035–1049

    Article  CAS  Google Scholar 

  37. Soergel P, Hertel H, Nacke AK, Klapdor R, Derlin T, Hillemanns P (2017) Sentinel Lymphadenectomy in Vulvar Cancer Using Near-Infrared Fluorescence From Indocyanine Green Compared With Technetium 99m Nanocolloid. Int J Gynecol Cancer 27(4):805–812. https://doi.org/10.1097/IGC.0000000000000996

    Article  PubMed  Google Scholar 

  38. Tax C, Rovers MM, De Graaf C et al (2015) The sentinel node procedure in early stage cervical cancer, taking the next step; a diagnostic review. Gynecol Oncol 139:559–567

    Article  Google Scholar 

  39. Uccella S, Gisone B, Stevenazzi G et al (2018) Laparoscopic sentinel node detection with ICG for early ovarian cancer: description of a technique and literature review. Eur J Obstet Gynecol Reprod Biol 221:193–194

    Article  Google Scholar 

  40. Uccella S, Nero C, Vizza E et al (2019) Sentinel-node biopsy in early-stage ovarian cancer: preliminary results of a prospective multicentre study (SELLY). Am J Obstet Gynecol 221:324e1–324e10

    Article  Google Scholar 

  41. Van Der Zee AG, Oonk MH, De Hullu JA et al (2008) Sentinel node dissection is safe in the treatment of early-stage vulvar cancer. J Clin Oncol 26:884–889

    Article  Google Scholar 

  42. Zeitoun J, Babin G, Lebrun JF (2019) Sentinel node and breast cancer: a state-of-the-art in 2019. Gynecol Obstet Fertil Senol 47:522–526

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Paul Buderath.

Ethics declarations

Interessenkonflikt

P. Buderath und R. Kimmig geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

Additional information

Redaktion

T. Fehm, Düsseldorf

L. Kiesel, Münster

R. Kimmig, Essen

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Buderath, P., Kimmig, R. Sentineltechnik mit ICG in der Gynäkologie. Gynäkologe 53, 463–466 (2020). https://doi.org/10.1007/s00129-020-04599-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00129-020-04599-y

Navigation