Zusammenfassung
Kinderwunschtherapien bei Frauen ab 40 Jahren haben eine begrenzte Erfolgschance. Die ovarielle Reserve und die Eizellqualität sind vermindert, die Chancen der „assisted reproduction technology“ (ART) kontinuierlich abnehmend. Die Stimulationsprotokolle zur ovariellen Stimulation unterscheiden sich nicht von denen bei jüngeren Patientinnen. Vorteile der verschiedenen Stimulationsprotokolle speziell für diese Altersgruppe konnten nicht gezeigt werden.
Abstract
Treatment of infertility in women over the age of 40 years is of limited success. The ovarian reserve is diminished in most cases as is the quality of oocytes and the chances of success with assisted reproduction technology (ART) steadily decrease with age. Stimulation protocols for controlled ovarian hyperstimulation (COH) are no different from those for younger patients. No advantages for any of the various stimulation protocols could be shown for this particular age group.
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Interessenkonflikt. T. Strowitzki und M. von Wolff geben an, dass kein Interessenkonflikt besteht. Der Beitrag enthält keine Studien an Menschen oder Tieren.
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Strowitzki, T., von Wolff, M. Ovarielle Stimulation bei der prä- und perimenopausalen Patientin. Gynäkologe 47, 258–262 (2014). https://doi.org/10.1007/s00129-013-3269-9
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DOI: https://doi.org/10.1007/s00129-013-3269-9