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Früherkennung des Endometriumkarzinoms

Early recognition of endometrial cancer

  • Leitthema
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Der Gynäkologe Aims and scope

Zusammenfassung

Das Endometriumkarzinom ist mit einer Inzidenz von 28/100.000 Frauen pro Jahr das häufigste Genitalkarzinom der Frau. Da die Prognose dieser Erkrankung bei frühzeitiger Diagnose im Stadium I mit einer Fünfjahresüberlebensrate von 85 % gut ist, konzentrieren sich wie bei allen soliden Karzinomen die klinischen Bemühungen auch beim Endometriumkarzinom darauf, diese Erkrankung zu einem möglichst frühen Zeitpunkt zu erkennen und zu behandeln. In der klinischen Praxis erfolgt die Diagnose eines Endometriumkarzinoms in der Regel im Rahmen der weiteren Abklärung einer symptomatischen Patientin, die sich aufgrund von Blutungsstörungen, meist einer Blutung in der Postmenopause, oder auffälligem Ausfluss vorstellt. Im vorliegenden Beitrag werden die Verfahren, die zur Früherkennung eines Endometriumkarzinoms zur Verfügung stehen, vorgestellt und ihre Wertigkeit kritisch diskutiert.

Abstract

Endometrial cancer is the most common genital cancer in women with an annual incidence of 28 per 100,000 women. Because the prognosis of this disease is good by early recognition in stage I with a 5-year survival rate of 85 %, the clinical efforts with endometrial cancer as with all solid tumors are concentrated on recognizing and treating this disease as early as possible. In the clinical practice as a rule the diagnosis of endometrial cancer is made within the framework of a further clarification of symptomatic patients presenting mostly with postmenopausal bleeding disorders or a conspicuous discharge. This article describes the procedures available for early recognition of endometrial cancer and the significance is critically discussed.

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- Einhaltung ethischer Richtlinien

Interessenkonflikt. P. Mallmann gibt an, dass kein Interessenkonflikt besteht. Alle im vorliegenden Manuskript beschriebenen Untersuchungen am Menschen wurden mit Zustimmung der zuständigen Ethikkommission, im Einklang mit nationalem Recht sowie gemäß der Deklaration von Helsinki von 1975 (in der aktuellen, überarbeiteten Fassung) durchgeführt. Von allen beteiligten Patienten liegt eine Einverständniserklärung vor.

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Mallmann, P. Früherkennung des Endometriumkarzinoms. Gynäkologe 47, 340–345 (2014). https://doi.org/10.1007/s00129-013-3260-5

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  • DOI: https://doi.org/10.1007/s00129-013-3260-5

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