Zusammenfassung
Das Erkrankungsrisiko ist bei der pandemischen und saisonalen Influenzavirusinfektion für Schwangere erhöht. Schwangere erkranken im Vergleich zu nichtschwangeren Frauen in jüngerem Alter, die Erkrankung verläuft schwerer, sie müssen häufiger hospitalisiert und intensivmedizinisch behandelt werden. Darüber hinaus sind vermehrt Todesfälle bei Schwangeren zu beklagen. Die neonatale Morbidität und Mortalität ist relevant erhöht, wenn Schwangere an einer Influenzavirusinfektion leiden. Die allgemeine Impfung von Schwangeren gegen Influenza ist eine attraktive Lösung zu Verhinderung der Krankheitslast und Mortalität bei den schwangeren Frauen und deren Kindern.
Abstract
For pregnant women influenza (seasonal and pandemic) may have a more severe clinical course, increased complication rate, and higher case fatality rate. Pregnant women are at younger age when hospitalized. There is an increased risk for adverse outcomes among infants born to mothers infected with influenza during pregnancy. Pregnant women should be considered a high priority for receipt of influenza vaccine with the aim of preventing both the illness and mortality in mother and infant.
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Interessenkonflikt
Der Autor gibt an, bei klinischen Studien zur Prüfung von Influenzaimpfstoffen im Kindes- und Jugendlichenalter für die Firmen GSK, München, und Novartis, Holzkirchen, als Leiter der klinischen Prüfung bzw. als Prüfarzt tätig zu sein. Er ist beratend für die Firma Astra Zeneca, Wedel im Bereich Influenzaimpfstoffe für Kinder und Jugendliche tätig.
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Knuf, M. Influenzainfektion in der Gravidität. Gynäkologe 44, 593–600 (2011). https://doi.org/10.1007/s00129-011-2775-x
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DOI: https://doi.org/10.1007/s00129-011-2775-x