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Hormontherapie in der Peri- und Postmenopause

Malignomrisiko

Hormone therapy during and post menopause

Risk of malignoma

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Der Gynäkologe Aims and scope

Zusammenfassung

Das Mammakarzinom sowie das Endometriumkarzinom und das Ovarialkarzinom sind hormonabhängige Malignome. Östrogene und Gestagene können proliferativ auf das Tumorwachstum wirken. Die Hormontherapie (HT) in der Peri- und Postmenopause kann das Risiko für hormonabhängige Malignomerkrankungen erhöhen oder verringern. Dargestellt wird der Einfluss einer HT auf das Risiko für Mamma-, Endometrium-, Ovarial-, Zervix- und Kolorektalkarzinome.

Abstract

Breast, endometrial, and ovarian cancers are endocrine-dependent. Estrogens and progestogens can have a proliferative effect on tumor growth. Hormone therapy during and after menopause can raise or lower the risk of a malignoma. This article explains its influence on the risk of mammary, endometrial, ovarian, cervical, and colorectal cancers.

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  1. Klinik für Frauenheilkunde und Geburtshilfe, Caritas-Krankenhaus St. Josef, Universität Regensburg, Landshuter Str. 63, 93053, Regensburg, Deutschland

    D. Noss &  O. Ortmann

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  1. D. Noss
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  2. O. Ortmann
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Correspondence to O. Ortmann.

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Noss, D., Ortmann, O. Hormontherapie in der Peri- und Postmenopause. Gynäkologe 43, 318–323 (2010). https://doi.org/10.1007/s00129-009-2470-3

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