Zusammenfassung.
Für die Behandlung von Patientinnen mit frühem Zervixkarzinom stehen laparoskopisch assistierte vaginale Operationsverfahren wie die laparoskopisch assistierte radikale vaginale Hysterektomie (LARVH) und die radikale vaginale Trachelektomie (RVT) zur Verfügung. Die Laparoskopie erlaubt eine sichere regionäre Ausbreitungsdiagnostik, insbesondere zur Evaluierung des wichtigsten Prognosefaktors für das Zervixkarzinom, des Lymphknotenstatus. Beide Methoden haben ihre onkologische Sicherheit in prospektiven Studien bewiesen. Die geringe Morbidität verbunden mit einer schnellen Rekonvaleszenz lassen sie für ausgewählte Patientinnen eine valide Alternative zur offenen radikalen Chirurgie des Zervixkarzinoms werden.
Abstract
For the treatment of early-stage cervical carcinomas, laparoscopic vaginal surgical methods include laparoscopically assisted radical vaginal hysterectomy and radical vaginal trachelectomy. Laparoscopy is safe for diagnosing local tumor extent, evaluating the main prognostic factors in cervical cancer, and assessing lymph node status. The oncologic safety of both techniques has been proven in prospective studies. Their low associated morbidity and fast recovery allow a valid alternative to open radical resection, for eligible patients.
Literatur
Dargent D (1987) A new future for Schauta’s operation through presurgical retroperitoneal pelviscopy. Eur J Gynaecol Oncol 8: 292–296
Spirtos NM (1992) Laparoscopic radical hysterectomy with paraaortic and pelvic lymph node dissection. Am J Obstet Gynecol 166: 864–865
Schneider A, Possover M, Kamprath S et al. (1996) Laparoscpy-assisted radical vaginal hysterectomy modified according to Schauta-Stoeckel. Obstet Gynecol 88: 1057–1060
Malur S, Possover M, Schneider A (2001) Laparoscopically assisted radical vaginal versus radical abdominal hysterectomy type II in patients with cervical cancer. Surg Endosc 15: 289–292
Dargent D, Brun JL, Roy M et al. (1994) La trachelectomie elargie (T.E.) une alternative a l hysterectomie redicale dans le traitement des cancers infiltrants developpes sur la face externe du col uterin. Jobgyn 2: 285–292
Hertel H, Köhler C, Elhawary T et al. (2002) Laparoscopic staging compared with imaging techniques in staging of advanced cervical cancer. Gynecol Oncol 87: 46–51
Hertel H, Köhler C, Michels W et al. (2003) Laparoscopic assisted radical vaginal hysterectomy (LARVH): prospective evaluation of 200 patients with cervical cancer. Gynecol Oncol 90: 505–511
Possover M, Stöber S, Plaul K, Schneider A (2000) Identification and preservation of the motoric innervation of the bladder in radical hysterectomy type III. Gynecol Oncol 79: 154–157
Dargent D, Martin X, Sacchetoni A, Mathevet P (2000) Laparoscopic vaginal radical trachelectomy: a treatment to preserve the fertility of cervical carcinoma patients. Cancer 88: 1877–1882
Mathevet P, Laszlo de Kaszon E, Dargent D (2003) Fertility preservation in early cervical cancer. Gynecol Obstet Fertil 31: 706–712
Covens A, Shaw P, Murphy J et al. (1999) Is radical trachelectomy a safe alternative to radical hysterectomy for patients with stage IA-B carcinoma of the cervix? Cancer 86: 2273–2279
Shepherd JH, Crawford RA, Oram DH (2001) Radical trachelectomy in early stage carcinoma of the cervix: outcome as judged by recurrence and fertility rates. BJOG 108: 882–885
Burnett AF, Roman LD, O’Meara AT, Morrow CP (2003) Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical carcinoma. Gynecol Oncol 88: 419–423
Schlaerth JB, Spirtos NM, Schlaerth AC (2003) Radical trachelectomy and pelvic lymphadenectomy with uterine preservation in the treatment of cervical cancer. Am J Obstet Gynecol 188: 29–34
Plante M, Renaud MC, Francois H, Roy M (2004) Vaginal radical trachelectomy: an oncologically safe fertility-preserving surgery. An update series of 72 cases and review of the literature. Gynecol Oncol 94: 614–623
Hertel H, Köhler C, Grund D et al. (2006) Radical vaginal trachelectomy (RVT) combined with laparoscopic pelvic lymphadenectomy: prospective multicenter study of 100 patients with early cervical cancer. Gynecol Oncol 103: 506–511
Boss EA, Golde RJ van, Beerendonk CC, Massuger LF (2005) Pregnancy after radical trachelectomy: a real option? Gynecol Oncol 99: 152–156
Plante M, Renaud MC, Hoskins IA, Roy M (2005) Vaginal radical trachelectomy: a valuable fertility-preserving option in the management of early-stage cervical cancer. A series of 50 pregnancies and review of the literature. Gynecol Oncol 98: 3–10
Interessenkonflikt
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hertel, H., Schneider, A., Altgassen, C. et al. Zervixkarzinom. Gynäkologe 41, 355–360 (2008). https://doi.org/10.1007/s00129-008-2131-y
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00129-008-2131-y
Schlüsselwörter
- Zervixkarzinom
- Radikale vaginale Trachelektomie (RVT)
- Laparoskopisch assistierte radikale vaginale Hysterektomie (LARVH)
- Lymphknotenmetastasierung