Abstract
This study aimed to investigate the dissipation, residues and dietary assessment of kresoxim-methyl in the application of Rosa Roxburghii and soil field using liquid chromatography-tandem mass spectrometry (LC–MS/MS). The results show that kresoxim-methyl in R. roxburghii samples was extracted by acetonitrile and purified by ethyl enediamine-N-propylsilane (PSA), while kresoxim-methyl in soil samples was extracted by acetonitrile and purified by octadecylsilyl solid phase dispersant (C18). 0.1% formic acid (v/v)-water–methanol solution was used as the mobile phase, LC–MS/MS exhibited a good linearity in the range of 0.001–10 mg L−1. The recoveries of R. roxburghii and soil matrix were 82.48%–102.55%, and the relative standard deviation (RSD) were 1.13%–4.21%. The limit of detection (LOD) and quantification (LOQ) of kresoxim-methyl in R. roxburghii and soil samples was 0.50 and 0.60 µg kg−1, respectively. The dissipation dynamics of kresoxim-methyl in R. roxburghii and soil followed the first-order kinetics, with the half-life of 4.28 and 4.41 days, respectively. The terminal residual amount of kresoxim-methyl in R. roxburghii and soil samples was 0.003–1.764 and 0.007–2.091 mg kg−1, respectively. The dietary intake risk assessment indicates that a risk quotient (RQ) for kresoxim-methyl based on the national estimated daily intake (NEDI) of 0.1995 mg was 0.79%, suggesting that the use of kresoxim-methyl on R. roxburghii at recommended dosage was safe to consumers. This study provides the theoretical basis for guiding the rational use of kresoxim-methyl in the production of R. roxburghii.
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Data Availability
The datasets generated or analyzed during the study are available from the corresponding author upon reasonable request.
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Funding
This work was supported by the National Natural Science Foundation of China (No. 32160656), the Science-Technology Support Program of Guizhou Province (No. [2021]YB243], the Hundred Level Talent Foundation of Guizhou Province (No. GCC [2022]023–1), and the Cultivation Program of Guizhou University (No. [2019]09).
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Zheng, H., Wu, Q. & Wu, X. The Dissipation Kinetics, Residue Level and Dietary Risk of Kresoxim-Methyl in Rosa roxburghii and Soil Based on the QuEChERS Method Coupled with LC–MS/MS. Bull Environ Contam Toxicol 111, 49 (2023). https://doi.org/10.1007/s00128-023-03771-z
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DOI: https://doi.org/10.1007/s00128-023-03771-z