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Dynamic Elimination of Enrofloxacin Under Varying Temperature and pH in Aquaculture Water: An Orthogonal Study

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Abstract

Orthogonal experiments were used to simulate the enrofloxacin (ENR) elimination dynamic in deeper water of aquaculture. Two factors at values common in fishery water (temperature of 20°C, 25°C, and 30°C; pH of 5, 7, and 9) were studied. The degradation of ENR in the nine treatment groups ranged from 44.7 to 80.1%. Variance analysis indicated that pH had a strong impact on the elimination of ENR, while temperature changes showed little effect. The ENR removal rate was highest at a combination of 25°C and pH 5. The optimal conditions of eliminating ENR were performed for exploring the generation of ciprofloxacin (CIP), which indicated that higher ENR concentrations led to the production of greater amounts of CIP. The half-time of ENR was increased 2.02-times in the ENR concentrations increasing from 20 to 2000 ng/mL. This study could increase our understanding of the behaviors of ENR and CIP during the aquaculture process.

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Acknowledgements

This work was supported by National Key R&D Program of China (2017YFC1600704), National natural science foundation of China (31802271), and Central Public-interest Scientific Institution Basal Research Fund, Freshwater Fisheries Research Center, CAFS (No. 2019JBFZ04).

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Author notes

  1. Longxiang Fang and Yiwen Zhou contributed equally to this work.

Authors and Affiliations

  1. Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, 214081, PR China

    Longxiang Fang, Chao Song & Jiazhang Chen

  2. Laboratory of Quality & Safety Risk Assessment for Aquatic Products On Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi, 214081, PR China

    Longxiang Fang, Chao Song & Jiazhang Chen

  3. Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing, 100000, PR China

    Longxiang Fang, Chao Song & Jiazhang Chen

  4. Department of Chemical Engineering, Tokyo University of Agriculture and Technology, Tokyo, 184-8588, Japan

    Yiwen Zhou

  5. Wuxi Fisheries College, Nanjing Agricultural University, Wuxi, 214081, PR China

    Zhuyu Huang, Chao Song & Jiazhang Chen

  6. Fisheries Engineering Institute, Chinese Academy of Fishery Sciences, Beijing, 100000, PR China

    Guang Yang & Tian Li

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  1. Longxiang Fang
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Correspondence to Jiazhang Chen.

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Fang, L., Zhou, Y., Huang, Z. et al. Dynamic Elimination of Enrofloxacin Under Varying Temperature and pH in Aquaculture Water: An Orthogonal Study. Bull Environ Contam Toxicol 106, 866–872 (2021). https://doi.org/10.1007/s00128-021-03199-3

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  • DOI: https://doi.org/10.1007/s00128-021-03199-3

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