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Toxicological Assessment of Intermediates in Natural Attenuation of p-Xylene to Marine Microalgae


The toxic effects of p-xylene, 4-methylbenzyl alcohol, p-methyl benzaldehyde, and p-toluic acid on two marine microalgae (Phaeodactylum tricornutum Bohlin, and Skeletonema costatum) were investigated. p-Xylene was the most toxic to Pha. tricornutum with a 96 h EC50 value of 6.76 mg L−1. Based on the 96 h EC50 values for two microalgae, the toxicity of the four chemicals, in descending order, was: p-xylene, p-methyl benzaldehyde, 4-methylbenzyl alcohol, then p-toluic acid. The results showed that the toxicity of the transformed products of p-xylene was lower than that of p-xylene.

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This work was supported by the National Marine Hazard Mitigation Service, Ministry of Natural Resources of the People’s Republic of China through its Commissioned Research Scheme (Grant No. 2018AA019).

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Correspondence to Fanping Meng.

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Li, F., Duan, W., Du, S. et al. Toxicological Assessment of Intermediates in Natural Attenuation of p-Xylene to Marine Microalgae. Bull Environ Contam Toxicol 103, 441–446 (2019).

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  • p-Xylene
  • Intermediates
  • Marine microalgae
  • Toxicity