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Characterization of Acute and Chronic Toxicity of DBP to Daphnia magna

Abstract

As a commonly used phthalate compound, di(n-butyl) phthalate (DBP) is an emerging group of polyvinyl chloride plasticizers. The acute toxicity of DBP has been extensively studied using the aquatic indicator organism, Daphnia magna. However, little is known about chronic and transgenerational toxicity of DBP. In this study, acute LC50 values were 3.04 mg/L (24 h) and 2.55 mg/L (48 h). Chronic toxicity tests in the case of maternal exposure to DBP revealed that DBP had negligible effects on growth and reproduction of F3 generation of D. magna, although the growth rate of body length and the intrinsic rate of increase were prominently reduced, to a pretty small extent. At specific concentrations, DBP generated beneficial effects on the parental generation of D. magna and no obvious impacts on the F1 generation. This study showed that maternal exposure to DBP did not cause any transgenerational effects on D. magna.

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Acknowledgements

This research was financially supported by the National Natural Science Foundation of China (No. 41501535), Special Program for Key Basic Research of the Ministry of Science and Technology, China (No. 2014FY210700), Liaoning Province Natural Science Foundation of China (201601387).

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Correspondence to Wen Zhao or Xi Xie.

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Wei, J., Shen, Q., Ban, Y. et al. Characterization of Acute and Chronic Toxicity of DBP to Daphnia magna. Bull Environ Contam Toxicol 101, 214–221 (2018). https://doi.org/10.1007/s00128-018-2391-8

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Keywords

  • Daphnia magna
  • Acute and chronic toxicity
  • Di(n-butyl) phthalate
  • Transgenerational toxicity